精神分裂症伴强迫症状的临床研究  

A clinical study on schizophrenia with obsessive-compulsive symptoms

作　　者：陈平周[1] 陈幼然[1] 张强 刘少文[1] 

机构地区：[1]汕头大学精神卫生中心,515063

出　　处：《神经疾病与精神卫生》2006年第6期438-440,共3页Journal of Neuroscience and Mental Health

摘　　要：目的分析伴强迫症状的精神分裂症临床特点及治疗效果,为临床诊断及治疗提供参考。方法对伴强迫症状的精神分裂症与不伴强迫症状的精神分裂症各38例进行对照分析,使用维思通抗精神病药物治疗,采用阳性及阴性症状量表(PANSS)、强迫症状量表(Y-BOCS)、Hamilton抑郁量表(HAMD)、Hamilton焦虑量表(HAMA)评定疗效。结果伴强迫症状的精神分裂症起病年龄早,起病隐袭,病程迁延,以阴性症状为主,住院时间长,治疗效果差,Y-BOCS、HAMD、HAMA等量表评分明显高于不伴强迫症状的精神分裂症,有显著性差异。结论伴强迫症状的精神分裂症,具有一定的异质性,单一使用抗精神病药物疗效差。Objective To investigate the clinical feature and treatment effect of schizophrenia patients accompanied with obsessive symptom, supply some evidence for clinical diagnosis and treatment. Methods 38 schizophrenia patients with obsessive symptom were compared with 38 schizophrenia patients without obsessive symptom. They receive treatment with Risperdal. The effect of treatment was evaluated by The Positive and Negative Syndrome Scale(PANSS),Yale-Brown Obsessive Compulsive Scale(Y-BOCS),Hamilton Depression Rating Scale for Depression (HAMD),Hamilton Rating Scale for Anxiety (HAMA).Results The schizophrenia patients accompanied with obsessive symptom have the features such as early onset, negative symptom as the main symptom, and long time in hospital ,poor treatment effect, the score of Y-BOCS、HAMD、HAMA higher than the patients without obsessive symptom. There are significant difference between two groups.Conclusions The schizophrenia patients accompanied with obsessive symptom have heterogeneity. The effect is poor using only antipsychotic drug treatment .

关 键 词：精神分裂症 强迫症状 

分 类 号：R749.3[医药卫生—神经病学与精神病学]