大豆磷脂对缺血再灌注家兔左室功能的影响  

Effects of soybean phospholipid on left ventricular function in ischemia reperfused rabbit

作　　者：汪长华[1] 余万桂[1] 万绍华[1] 张道明[1] 晏年春[1] 

机构地区：[1]湖北省卫生职工医学院生理学教研室

出　　处：《心功能杂志》1996年第4期203-206,共4页

摘　　要：本文报道缺血再灌注时家兔左室功能的变化及大豆磷脂对它的影响。结果显示：结扎冠脉左室支中点４５ｍｉｎ、再灌注１８０ｍｉｎ时，左室收缩功能和舒张顺应性呈渐进性降低。在结扎前和再灌注即刻以脂质体形式补充大豆磷脂可减轻左室收缩和舒张功能的降低，并可降低血浆乳酸脱氢酶活性。提示：大豆磷脂对缺血再灌注时家兔左室功能的损伤具有保护作用。This paper reports the effect of soybean phospholipid on the left ventricular function during ischemia reperfusion in rabbits in vivo The results showed that left ventricular systolic function and left ventricular diastolic compliance decreased progressively during 45 min of ischemia and 3 h of reperfusion The supple of soybean phospholipid before ischemia and at the beginning of reperfusion could inhibit the decrease of left ventricular systolic function and left ventricular diastolic compliance and decrease the activity of LDH in plasma The results indicated that soybean phospholipid has a protective effect of left ventricular function in ischemia reperfused rabbit

关 键 词：再灌流损伤 大豆磷脂 心室功能 左 心肌缺血 

分 类 号：R542.202[医药卫生—心血管疾病]