常压模拟高住低练对大鼠RBC、Hb及HCT的影响  

Effect of Simulated HiLo Training on RBC, Hb and HCT of Rats

作　　者：周桔[1] 瞿树林[1] 汤长发[1] 张沙骆[1] 林喜秀[1] 刘文峰[1] 刘铭[1] 

机构地区：[1]湖南师范大学体育学院,湖南长沙410012

出　　处：《中国体育科技》2007年第1期119-121,共3页China Sport Science and Technology

摘　　要：目的探讨常压模拟高住低练对大鼠RBC、Hb及HCT的影响。方法60只SD大鼠随机分成两大组对照组(Ⅰ)和运动组(Ⅱ)。其中,Ⅰ分为常氧组(A)、高住8h组(B)和高住12h组(C);Ⅱ分为常氧运动组(D)、高住8h运动组(E)和高住12h运动组(F)。D、E、F组大鼠每天在坡度为0的动物跑台上以25m/min的速度训练1h。训练完后,将B、E组和C、F组放入氧浓度为12.5%(相当于海拔4000m)的低氧舱内8h和12h。实验期为4w,5d/w。实验后取血进行全血红细胞计数(RBC)、血红蛋白(Hb)、红细胞压积(HCT)检测。结果B组和C组RBC、Hb、HCT值显著上升(P<0.001);D组和E组RBC、Hb、HCT值显著下降(P<0.001);B组与E组比较,3项指标均具有高度显著性差异(P<0.001)。结论模拟高原环境能够使SD大鼠RBC、Hb及HCT值显著增加,实验采用的模拟高住低练训练模式使SD大鼠RBC、Hb及HCT值降低,且高住8h组和高住12h组、高住8h运动组和高住12h运动组之间差异无显著性。The purpose of this study was to discuss the effect of simulated HiLo training on RBC Hb and HCT of Rats. Sixty male Sprague-Dawley rats were randomly divided into two groups： control group （ Ⅰ ） and training group （ Ⅱ ） （n= 10）. Group Ⅰ was divided into normoxia group （A）, living-high for 8h （B）, living-high for 12h （C）. GroupⅡ was divided into normoxia training （D）, training on living-high for 8h （E） and training on living-high for 12h （F）. The rats of group D.E and F were introduced to treadmill running on an incline of 0 at 25m/min for 1h. After training, the rats of group B, E, C and F were exposed to hypoxic chamber with 12.5% concentrations of oxygen （equal to altitude of 4000m） for 8h and 12h every day for 4 weeks. The red blood cell （RBC）, hemoglobin （Hb） and haematocrit （HCT） were determined. The result showed that the increase of RBC Hb and HCT in group B and C were significant. The reduction of RBC, Hb and HCT in group D and E were significant. Comparison between group B and E was significant. It concluded that the simulated hypoxia could increase the level of RBC Hb and HCT, while the simulated HiLo Training could decrease the level of RBC Hb and HCT. The comparisons among the living-high for 8h and living-high for 12h, and training living-high for 8h and training living-high for 12h were not significant.

关 键 词：高住低练 血红蛋白 红细胞计数 压积 血液化学分析 动物实验 鼠 

分 类 号：G804.2[文化科学—运动人体科学]