内蒙古朱开沟遗址古代居民线粒体DNA分析  

Mitochondrial DNA analysis of remains from Zhukaigou archaeological site in Inner Mongolia

作　　者：王海晶[1] 常娥[1] 蔡大伟[1] 张全超[1] 周慧[1] 朱泓[1] 

机构地区：[1]吉林大学边疆考古研究中心古DNA实验室

出　　处：《吉林大学学报（医学版）》2007年第1期5-8,共4页Journal of Jilin University：Medicine Edition

基　　金：国家基础科学人才培养基金资助课题(J530184)

摘　　要：目的:探讨内蒙古朱开沟古代居民的遗传关系。方法:对9例保存较好的个体牙齿的线粒体基因组的高可变一区进行扩增和测序,与内蒙古饮牛沟古代人群及现代亚洲人群对比进行系统发育分析,并推测单倍型类群归属。结果:获得7例朱开沟遗址古代居民线粒体基因组高可变一区364 bp的序列,共检测出15个突变位点,界定7种单倍型,并归属到单倍型类群。结论:朱开沟古代居民在母系遗传上与其后的饮牛沟墓地古代居民及现代内蒙古地区人群关系密切,内蒙古中南部地区人群母系遗传结构具有连续性。Objective To assess the genetic affinities of the population from the Zhukaigou archaeological site in Inner Mongolia. Methods The mitochondrial DNA hypervariable region Ⅰ （HVR Ⅰ ） in teeth of 9 individuals were amplified and sequenced. Different phylogenetic analyses were performed using mtDNA sequences among the ancient population, the Yinniugou ancient population and several modern Asian populations. The sequences were primarily assigned into each mtDNA haplogroups, and compared with modern populations. Results Fragments of mtDNA HVR I , 364 bp in length, were recovered from 7 individuals from the Zhukaigou archaeological site. 7 sequence types and 15 polymorphism sites were found. Haplogroup distributions of the ancient individuals were investigated according to variations in the HVR Ⅰ sequence. Conclusion The matrilineal genetic structure of the Zhukaigou site population is close to that of the later Yinniugou population and modern populations in this area. This aDNA study shows the continuity of the matrilineal genetic structure in the populations of the south central Inner Mongolia.

关 键 词：朱开沟遗址 DNA 线粒体 古DNA系统发育分析 

分 类 号：Q987[生物学—遗传学]