急性白血病患者医院真菌感染的临床分析  

Nosocomial Fungal Infection among Inpatients with Acute Leukemia:A Clinical Analysis

作　　者：邵剑峰[1] 林茂芳[2] 钟永根[1] 刘忠民[1] 傅佳萍[1] 封蔚莹[1] 

机构地区：[1]绍兴市人民医院,浙江绍兴312000 [2]浙江大学医学院附属第一医院,浙江杭州310003

出　　处：《中华医院感染学杂志》2007年第1期29-31,共3页Chinese Journal of Nosocomiology

摘　　要：目的了解医院真菌感染的临床特点及防治对策,探讨真菌引起医院感染的原因和易感因素,制定预防和控制医院真菌感染的措施。方法对178例急性白血病患者医院真菌感染进行回顾性调查分析。结果急性白血病患者医院真菌感染39例,真菌感染率为21.91%,急性白血病患者医院真菌感染率≥60岁组高于<60岁组,中性粒细胞数≥0.5×109/L组真菌感染率高于中性粒细胞数<0.5×109/L组,所有病例感染前均使用抗菌药物。结论积极治疗原发病;提高中性粒细胞数,严格按规范使用抗菌药物,对预防医院真菌感染有十分重要的意义。OBJECTIVE To analyze the risk factors, clinical characteristics and prevention countermeasures of nosocomial fungal infection in patients with acute leukemia. METHODS To adopt investigation way to review and analyze the clinical data Of nosocomial fungal infection in 39 cases from 178 acute leukemia inpatients. RESULTS The nosocomial fungal infection rate was 21. 91%. The nosocomial fungal infection rate in elderly group was higher than that of younger group, and in granulocytosis group （≥0.5 × 10^9/L） was higher than that of 〈0.5 × 10^9/L granulocyte group. Antibiotics were used in all the patients before onset of nosocomial fungal infection. CONCLUSIONS The key to reduction of nosocomial fungal infection is to cure underlying diseases, increase granulocyte and choose antibiotics correctly.

关 键 词：医院真菌感染 白血病 急性 

分 类 号：R733.7[医药卫生—肿瘤]