L-高丝氨酸的合成  

Synthesis of L-homoserine

作　　者：陶德良[1] 邓燕[1] 谢维跃 蒋佑清 贺全国[1] 

机构地区：[1]湖南工业大学湖南省绿色包装与生物纳米技术应用重点实验室,湖南株洲412008 [2]湖南轻工研究院,湖南长沙410015

出　　处：《化工时刊》2007年第1期33-34,共2页Chemical Industry Times

基　　金：湖南省普通高校青年骨干教师培训计划资助(2005~2008)

摘　　要：以L-蛋氨酸为原料与碘甲烷在水溶液中于30℃搅拌反应24h，减压浓缩；加入碳酸氢钾回流10h，减压蒸干；溶解在甲醇中，用盐酸调pH值为5—6，即得L-高丝氨酸，总收率65．3％。对产品进行了红外光谱、核磁共振和质谱表征。L - homoserine was synthesized using L - methionine and methyl iodide as raw materials in water. The solution was stirred at 30℃ for 24 hours, concentrated in vacuo. Potassium hydrogen carbonate was added and refluxed in aqueous solution for 10 hours, evaporated in vacuo. The product was dissolved in methanol at pH 5 - 6. The yield of L - homoserine was summed up to 65.3 %. The product was verified by IR, 1HNMR and MS characterization.

关 键 词：L-高丝氨酸 合成 L-蛋氨酸 

分 类 号：TQ922.9[轻工技术与工程—发酵工程]