多效胃镜乳的处方改进及稳定性考察  

Improvement and stability of multi-effect gastroscope emulsion

作　　者：杨政[1] 于西全 晏明[3] 

机构地区：[1]福建省立医院药剂科,福建福州350001 [2]南京军区福州总院药剂科,福建福州350025 [3]第二军医大学,学员上海200433

出　　处：《药学实践杂志》2007年第1期26-30,共5页Journal of Pharmaceutical Practice

摘　　要：目的:改进多效胃镜乳的处方,提高多效胃镜乳的稳定性,控制制剂的质量。方法:通过外观质量、显微镜检、离心试验、耐寒耐热试验、常温留样以及含量测定等为指标,考察不同的乳化剂对多效胃镜乳质量的影响,确定最优处方。结果:以0．8％司盘-80、1．6％西黄蓍胶和5％司盘-80、2％CMC-Na配制的多效胃镜乳,稳定性好。结论:改进后的多效胃镜乳处方可应用于制剂生产。Objective： To enhance the stability and control quality of the muhi-effect gastroscope emulsion by improving the prescription of emulsion. Methods： The different prescriptiones of the multi-effect gastroscope emulsion were tested and evaluated by microscopy, centrifugal experiment, cold-resistant/heat-resistant experiment, room temperature storage test as well as the content-determination. Results： The emulsion with 0.8% span-80, 1.6% tragacantha or with 5% span-80, 2% CMC-Na has a good stability. Conclusion： The prescriptions of the multi-effect gastroscope emulsion can be applied to preparation production.

关 键 词：多效胃镜乳 处方改进 稳定性 

分 类 号：R943[医药卫生—药剂学]