边远地区儿童维生素A营养状况  

Nutritional status of vitamin A in children among remote area.

作　　者：谈藏文[1] 马官福[1] 林良明[1] 刘玉琳[1] 刘敏[1] 刘春燕[1] 王力[1] 

机构地区：[1]首都儿科研究所,北京100020

出　　处：《中国儿童保健杂志》2007年第1期25-27,共3页Chinese Journal of Child Health Care

基　　金：联合国儿童基金会资助(CRQ00003339-0)

摘　　要：【目的】了解边远地区儿童维生素A(vitamin A,VA)状况。【方法】进行眼部临床症状检查、视力情况问卷和血清VA测定。评价标准结膜干燥:任何阶段的结膜干燥性变化;夜盲:日间视力正常而低照明条件下视物困难。维生素A缺乏(VAD):血清VA值≤0.35μmol/L;亚临床维生素A缺乏(SVAD):0.35<血清VA值≤0.70μmol/L;可疑SVAD:0.70≤血清VA值≤1.05μmol/L[2]。VAD公共卫生问题:某地区VAD率>5.0%。SVAD公共卫生问题:轻度某地区夜盲率<1.0%,且2.0%≤SVAD率≤10.0%。中度1.0%≤某地区夜盲率<5.0%,且10.0%≤SVAD率<20.0%。【结果】儿童结膜干燥和夜盲率均为0.1%。以血清VA含量判断VAD、SVAD、可疑SVAD患病率分别为0.7%、11.7%、39.2%。广西、青海、内蒙、新疆、云南、贵州六省儿童SVAD患病率均>10%。SVAD患病率随所在地区海拔高度的增加而增高。儿童血清VA均值为(1.06±0.33)μmol/L,以广西最低。血清VA水平随其所在地区海拔高度的增加而降低。新疆的托克逊、青海的民和、贵州的普定和遵义、广西的贵港、内蒙的包头和依金霍格旗存在不同程度的VAD和SVAD公共卫生问题。【结论】边远贫困地区是我国VAD和SVAD公共卫生问题的重点地区,应给予干预。[Objective] To explore the status of vitamin A in children among remote area. [Methods] To examine clinical symptom of eye ,interview with questionnaire vision information and serum level of vitamin A measurement for children. The evaluate standard ： Xerophthalmia was defined as the change of conjunctiva xeransis in any phases. Night blindness refered to the difficulty of vision during nights. The cut-off value for vitamin A deficiency（VAD）, subclinical vitamin A deficiency（SVAD） and Suspicious SVAD were defined as ≤0, 35 μmol/L,0.350.70 μmol/L and 0.70～ 1.05 μmol/L,respectively. Mild public health problem of SVAD： Incidence of night blindness was 〈 1.0% and incidence of SVAD was 2.0 %～ 10.0% in some area; middle of public health problem of SVAD： Incidence of night blindness was 1.0%～ 5.0% and incidence of SVAD 10.0%～20.0% in some area. [Results] Incidence of xerophthalmia and Night blindness with children are 0.1%. Incidence of VAD; SVAD and suspicious SVAD were 0.7% ,11.7% ,39.2%, respectively. Incidence of SVAD were over 10% in Guangxi,Qinghai,Neimeng,Xinjiang, Yunnan,Guizhou. Level of serum VA was decreased with the increase of height above sea level. There are public health problem of VAD and SVAD in difference degree in Some area of Guangxi, Qinghai, Neimeng, Xinjiang, Guizhou. [Conclusions] Remote poverty-stricken rural areas is severity region for VAD and SVAD of public health problem . VA supplementation is urgently needed for the children in there.

关 键 词：维生素A 边远地区 公共卫生问题 

分 类 号：R153.2[医药卫生—营养与食品卫生学]