经颈总动脉注射降纤酶和普鲁卡因治疗脑梗死的疗效  

The observation on therapeutic efficacy of cerebral infarction with defibrase and procaine injection via common carotid artery

作　　者：张志 李宝琴 侯宪云 

机构地区：[1]番禺区大岗人民医院内科,广东广州511470

出　　处：《实用医药杂志》2007年第2期136-137,共2页Practical Journal of Medicine & Pharmacy

摘　　要：目的探讨经颈动脉加压注射降纤酶和普鲁卡因与常规静脉用药治疗脑梗死的疗效及其时效关系。方法64例脑梗死患者随机分为两组:对照组静脉滴注降纤酶、低分子右旋糖酐、舒血宁注射液和脑复康;试验组在静脉滴注上述药物的基础上加经颈总动脉加压注射降纤酶和普鲁卡因,比较两组的有效率,以及试验组的病程与疗效的关系。结果试验组的有效率为93.8%,其中发病24h以内患者的治愈率为72.7%,发病24h以上者治愈率为28.6%;对照组的有效率为71.9%,试验组与对照组比较有显著性差异。结论尽早经颈动脉注射上述药物可明显提高脑梗死的疗效。Objective To compare therapeutic effects of defibrase and procaine injection via common carotid artery therapy with routinely intravenous drip,and to explore their time- response relationship. Methods 64 cases of this disease was divided into two groups randomly.In control group, intravenous drip of defibrase, low molecular dextran, ShuXueNin injection and Piracetam were taken, but in experiment groups, added defibrase and procaine injection via common carotid artery therapy to abovementioned venous drugs.Authors compared efficacy of two groups and relationship between illness progress and curative effect.Results 93.8% of the patients in experiment groups were improved. When in 24 hours 72.7% of patients was cured, but only 28.6% of the patients cured after 24 hours.The effective rate was 71.9% in control group.Experiment group＇ effective rate was obviously superior to that in control group.Conclusion Early defibrase and procaine injection via common carotid artery could highly improve treatment effects of cerebral infarction.

关 键 词：脑梗塞 降纤酶 普鲁卡因 颈总动脉 

分 类 号：R743.33[医药卫生—神经病学与精神病学]