母儿ABO血型不合的产前诊断  

Prenatal diagnesis of ABO incompatibility

作　　者：邵振堂 刘慧 张兴安 王雅琴 陈敬琴 

机构地区：[1]南京市妇产医院

出　　处：《中国优生与遗传杂志》1996年第6期44-46,共3页Chinese Journal of Birth Health & Heredity

摘　　要：本文测定了３０２例Ｏ型足月孕妇的血清ＩｇＧ抗体效价及其新生儿血型、体重、血红蛋白、红细胞、血清胆红素。将３０２对母儿分为ＡＢＯ血型不合与相合二组。统计结果表明，两组的孕妇血清ＩｇＧ抗体效价无明显差别（Ｐ＞０．０５）。两组的新生儿体重、血红蛋白、红细胞、血清胆红素亦无明显差别（Ｐ＞０．０５），血清胆红素与孕妇抗体效价无明显相关（ｒ＝０．０７８５，Ｐ＞０．０５）。另外测定了４０例１６－３６孕周的Ｏ型孕妇血清ＩｇＧ抗体效价及其胎儿血型。资料显示，仅根据孕妇血清ＩｇＧ抗体效价不能诊断ＡＢＯ血型不合及预测ＡＢＯ溶血病，产前测定胎儿血型具有重要价值。Objective:Our purpose was to find index of correct prenatal diagnosis of ABO incompatibility.All mothers and newborns were divided into two groups according to blood typing,ABO compatibility and ABO incompatibility.Results:We measured maternal IgG titre in 342 cases and the blood type of the newborns in 302 and fetuses in 40,and body weight,hemoglobi,erythrocyte count,bilirubin of the newborns.It showed that difference between IgG titre from compatible and that from incompatible was not significant(P>0.05),The differences between body weight,hemoglobin,erythrocyte count bilirubin of newborns from compatible and that from incompatible were not significant(P>0.05).Correlation between IgG titre and bilirubin was not significant(r=0.0785,P>0.05).Conclusion:ABO incompatibility and hemolysis were not forecasted Only according to IgG titre,Blood typing of the fetuses was of importance in the diagnosis of ABO incompatibility and in management of ABO hemotylytic disease of the newborns and other fetus disorders.

关 键 词：血型不合 ABO血型不合 胎儿 血型 产前诊断 

分 类 号：R714.5[医药卫生—妇产科学] R556.62[医药卫生—临床医学]