利多卡因在肝血管瘤介入治疗中的价值  

Value of lidocaine in interventional therapy for liver hemangioma

作　　者：陈晓良[1] 周培华[1] 张斌[1] 余俭[1] 龚水根[2] 陈蓉[2] 

机构地区：[1]重庆市肿瘤医院影像科,重庆400030 [2]第三军医大学大坪医院野战外科研究所影像诊断科,重庆400042

出　　处：《第三军医大学学报》2007年第6期553-554,共2页Journal of Third Military Medical University

摘　　要：目的采用肝血管瘤介入治疗的不同方法,探讨利多卡因在肝血管瘤介入治疗中的价值。方法将36例肝血管瘤病例分为两组,A组(19例)在动脉栓塞前,先经动脉灌注利多卡因,再将利多卡因与平阳霉素、碘油混合后碘油和药物的乳化剂注入;B组(17例)为对照组,动脉栓塞过程中,不用利多卡因。观察治疗过程中患者的反应和病灶碘油和药物的乳化剂的填充情况。结果两组中重度不良反应比例不同,利多卡因组为10.5%,对照组为41.2%。病灶碘油和药物的乳化剂的完全填充率利多卡因组为100%,对照组为79.2%。结论肝血管瘤介入治疗过程中,应用利多卡因可以提高介入治疗的成功率,降低不良反应,取得较好疗效。Objective To investigate the value of lidocaine interventional therapy for liver hemangioma. Methods Thirty-six patients with liver hemangioma were divided into group A （ n = 19） receiving lidocaine prior to transcatheter arterial embolization （TAE）, then the emulsion of pingyangmycin, lidocaine and iodized oil; group B （ n = 17） receiving the emulsion of pingyangmycin and iodized oil except lidocaine. We observed that the reaction of all patients after TAE and how much the hemangioma was filled. Results The rate of serious complications was 10.5% in group A and 41.2% in group B. The hemangioma filhng with emulsion was 100% in group A and 79.2% in group B. Conclusion Intraarterial pharmacotheraphy of lidocaine in interventional therapy for liver hemangioma may promote the chance of success and reduce serious complications, result in good effect.

关 键 词：肝血管瘤 介入治疗 利多卡因 价值 

分 类 号：R732.2[医药卫生—肿瘤] R735.7[医药卫生—临床医学]