乳腺癌两种途径介入化疗并发症的临床分析  

Clinical analysis of the complications of interventional chemotherapy for breast cancer by two different ways

作　　者：朱晓琴[1] 罗凤[1] 

机构地区：[1]重庆医科大学附属第一医院普外科,重庆400016

出　　处：《重庆医科大学学报》2007年第3期325-327,共3页Journal of Chongqing Medical University

摘　　要：目的:分析两种介入途径治疗乳腺癌所产生的并发症,旨在合理选择介入化疗的途径,降低并发症的发生。方法:乳腺癌患者91例,分为两组:经尺动脉途径插管行介入化疗组28例(简称尺动脉组)和经股动脉途径插管行介入化疗组63例(简称股动脉组),两组分别在DSA室于局麻下经尺动脉和股动脉插管,将导管置于锁骨下动脉与胸廓内动脉开口交界处的近侧,灌注化疗药物,尺动脉组留置导管行化疗1￣2个疗程,股动脉组一次性灌注化疗药物后即拔管,观察并分析两种途径所产生的并发症。结果:尺动脉组发生并发症11例,发生率39.29%;股动脉组发生并发症4例,发生率6.35%(χ2=12.98,P<0.01),两组差异具有显著性意义。结论:经股动脉介入化疗发生的并发症明显低于经尺动脉组,其安全性较高。Objective：To analyze the complications of interventional chemotherapy for breast cancer by two different ways to rationally select interventional chemotherapy ways with low risks of complications.Methods：A total of 91 cases of breast cancer were divided into 2 groups,interventional chemotherapy group through ulnar artery （i.e.,ulnar artery group）with 28 cases and interventional chemotherapy group through femoral artery（i.e.,femoral artery group）with 63 cases.Both groups were operated with local anesthesia in DSA room,and the chemotherapeutic drugs were perfused when the catheters were inserted into the proximal side of the cross of infraclavicular artery and internal thoracic artery.The catheters in ulnar artery group were kept for 1 to 2 therapeutic courses,but not in femoral artery group.The complications were observed and analyzed.Results：The occurrence rate of complication in ulnar artery group was 39.29%（11cases）,which was significantly higher than that （6.35%,4 cases）of femoral artery group （χ^2=12.9g,P〈0.01）.Conclusion：The occurrence rate of complication in femoral artery group was significantly lower than that of ulnar artery group ,which indicated that the femoral artery way had higher security for breast cancer.

关 键 词：乳腺癌 介入化疗 并发症 

分 类 号：R737.9[医药卫生—肿瘤]