颅内碰撞瘤  

Intracranial collision tumor

作　　者：汤国才[1] 朴月善[1] 赵兰[1] 杨虹[1] 卢德宏[1] 

机构地区：[1]首都医科大学宣武医院病理科,北京100053

出　　处：《中国现代神经疾病杂志》2007年第1期52-56,共5页Chinese Journal of Contemporary Neurology and Neurosurgery

摘　　要：目的介绍颅内碰撞瘤的组织病理学特点和临床表现,以提高对该病的认识。方法对2006年7月13日收治的1例碰撞瘤患者的临床表现、影像学特点、神经病理学结果等资料进行回顾性分析。结果主要临床表现为间歇性头痛、发作性意识丧失、抽搐;头部MRI检查显示左侧额叶占位;组织病理学观察可见肿瘤组织中的主要成分为胶质母细胞瘤,次要成分为细胞角蛋白和甲状腺转录因子-1表达阳性的癌组织。结论对于常见肿瘤组织中出现的异常成分应考虑由其他系统转移而来,须详细追问病史并对患者做进一步的体格检查,以避免误诊。Objective To introduce the histopathological and clinical features of intracranial collision tumor, and improve the understanding of this disease. Methods Retrospective study was performed to analyse the clinical manifestations, imaging characteristics and neuropathological findings of one patient suffered with intracranial collision tumor in July 13th, 2006. Results The main clinical manifestations were intermittent headache, paroxysmal unconsciousness and twitching. The cranial MRI showed a space occupying lesion in left frontal lobe. Histopathological examination revealed that the most part of the lesion was glioblastoma, and the other part was carcinoma with immunopositive for cytokeratin （CK） and thyroid transcription factor-1 （TTF-1）. Conclusion When encountering common tumors with abnormal component, it is suggested to consider metastatic carcinoma and perform overall physical examination as well as review the history in detail in order to avoid misdiagnosis.

关 键 词：甲状腺肿瘤 肺肿瘤 胶质母细胞瘤 免疫组织化学 

分 类 号：R739.4[医药卫生—肿瘤]