实验比格犬群发性泌尿系统结石的诊治  

Diagnosis and Treatment of Population Urinary Stone Disease in a Laboratory Beagle Dog Colony

作　　者：邱正良[1] 赵太云[1] 洪宝庆[1] 孙岩松[1] 刘源[1] 曾林[1] 王俊朝[1] 江其辉[1] 

机构地区：[1]军事医学科学院实验动物中心,北京100071

出　　处：《中国比较医学杂志》2007年第2期63-66,F0002,共5页Chinese Journal of Comparative Medicine

摘　　要：目的寻找某实验比格犬繁育基地群发性泌尿系统结石的病因及其有效的防治措施。方法采用临床诊断、病理诊断、结石成分分析、饲料成分分析、回顾性调查分析等手段以及综合的处理措施。结果经分析发现该群发性泌尿系统结石是由肉粉引起的尿酸盐结石,通过碱化尿液、降低血尿酸和去除病因等方法后,全群得到了有效的治疗。结论该肉粉是引起此次群发性泌尿系统结石的主要原因,由尿酸盐引起的、未发生器质性病变的尿路结石症可以治愈。Objective To elucidate the etiological factors inducing population urinary stone disease in a Beagle dog farm, and to set up an effective treatment and prevention of this disease. Method In this study clinical and pathological examinations were carried out, and to make diagnosis, composition of the urinary stones and feed were analyzed. Retrospective study was made and successful treatment was achieved. Result It was found that the etiological factor leading to the urinary stone disease was meat powder included in the feed for the animals. The urinary stones were composed of salt of urid acid. By alkalinizing the urine, degrading the urate in the blood and removing it, all Beagle dogs in that Beagle dog farm were effectively cured. Conclusion The meat powder for animals was found to be the only etiological factor and the degenerative nephritis owing to salt of uric acid caused urinary lithiasis, which has well been cured at the beginning and intermediate stage of the disease.

关 键 词：犬 比格 泌尿系统结石 群发病 

分 类 号：R-33[医药卫生]