72例老年人恶性淋巴瘤治疗分析  

Analysis of treatment of 72 aged patients with malignant lymphoma

作　　者：李晓莉[1] 崔淑珍[1] 刁春香 

机构地区：[1]哈尔滨医科大学附属第三医院

出　　处：《中华老年医学杂志》1996年第4期214-216,共3页Chinese Journal of Geriatrics

摘　　要：目的探讨提高老年人恶性淋巴瘤疗效的治疗方法。方法回顾性分析７２例老年人恶性淋巴瘤治疗的近期疗效及１、３、５年生存率及毒性反应发生率。结果老年人恶性淋巴瘤的综合治疗优于单纯化疗，其缓解率（ＣＲ＋ＰＲ）分别为４５％及９２％（Ｐ值＜０．０１）。采用中等剂量的联合化疗及放疗，其近期疗效及１、３、５年生存率及毒性反应发生率与非老年人恶性淋巴瘤差异无显著性（Ｐ值＞０．０５）。结论对老年人恶性淋巴瘤应采取积极的综合治疗，联合化疗及放疗的剂量要适当。ohjective How to improve the therapeutic effectiveness and to reduce the toxicity in treatinent of aged patients with malignant lymphoma. Methods Seventy two aged patients with malignant lymphoma, from June 1975 to December 1990, were retrospectively analysed in comparison with 760 non-aged patients with malignant lymphoma. Results This study demonstrated that chemotherapy combined with radiotherapy was superior to chemotherapy alone in aged malignant lymphoma(P<0. 01). The response rate, 1- , 3-and 5-yr survival rates and sidle effect rate of intermediate dose combined chemotherapy and radiotherapy were equivalent to those of non-aged patients with malignant lymphoma(P> 0. 05). Conclusions Treatment with appropriate doses of combined chemotherapy and radiotherapy should be adopted for the aged patients with malignant lymphoma.

关 键 词：淋巴瘤 治疗 死亡率 老年人 

分 类 号：R733.405[医药卫生—肿瘤]