一种稳定性过氧乙酸消毒性能试验观察  

EXPERIMENTAL OBSERVATION ON DISINFECTION PROPERTY OF A STABLE PERACETIC ACID

作　　者：钟昱文[1] 黄美卿[1] 王冰姝[1] 张里君[1] 柯昌文[1] 邢浩 

机构地区：[1]广东省疾病预防控制中心,广州510300 [2]广州君和实业有限公司

出　　处：《中国消毒学杂志》2007年第2期132-134,共3页Chinese Journal of Disinfection

摘　　要：目的了解一种稳定性液体过氧乙酸杀菌效果及其理化性能。方法用悬液定量杀菌试验和理化分析方法进行了实验室观察。结果该稳定性过氧乙酸产品有效含量达到185 g/L,于室温(25℃)储存12个月,其含量下降率为9.63%,储存18个月,其含量仍≥150 g/L。以含50 mg/L过氧乙酸水溶液对悬液内的大肠杆菌和铜绿假单胞菌作用3 min,对金黄色葡萄球菌作用5 min,杀灭对数值均>5.00。以含200 mg/L过氧乙酸水溶液对悬液内的白色念珠菌作用5 min,杀灭对数值>4.00。以含500 mg/L过氧乙酸水溶液对悬液内枯草杆菌黑色变种芽孢作用8 min,杀灭对数值>5.00。结论该液体过氧乙酸储存性能稳定,对细菌繁殖体、真菌和细菌芽孢均具有良好的杀灭效果。Objective To know the germicidal efficacy and physicechemical properties of a stable liquid peracetic acid. Methods Suspension quantitative germicidal test and physicochemical analysis method were used to carry out laboratory observation. Results The available content of the stable peracetic acid product attained 185 g/L. After storing at room temperature （25℃） for 12 months, its content decreased by 9.63% and its content was still ≥150 g/L after storing for 18 months. The killing logarithm values of Escherichia coli and Pseudomonas aeruginosa in suspension exposed to the water solution containing 50 mg/L peracetic acid for 3 min and Staphylococcus aureus exposed for 5 min were 〉5.00. The killing logarithm value of Candida albicans in suspension exposed to the water solution containing 200 mg/L peracetic acid for 5 rain was 〉4.00 and that of spores ofBacullus subtilis var. niger in suspension exposed to the water solution containing 500 mg/L peracetic acid for 8 min was 〉 5.00. Conclusion The liquid peracetic acid is stable during storing and has good efficacy in killing vegetative forms of bacteria, fungi and bacterial spores.

关 键 词：过氧乙酸 稳定性 悬液法 杀菌效果 细菌繁殖体 细菌芽孢 

分 类 号：R187.2[医药卫生—流行病学]