肿瘤干细胞及肝癌肿瘤干细胞  

Cancer Stem Cells and Hepatocarcinoma Stem Cells

作　　者：张世光[1] 成玉[1] 高英堂[2] 杜智[2] 陈力[1] 

机构地区：[1]南开大学生命科学学院,天津300071 [2]天津市第三中心医院,天津300170

出　　处：《细胞生物学杂志》2007年第1期6-10,共5页Chinese Journal of Cell Biology

基　　金：天津市重点科技攻关专项(No.05YFSJSF02500);天津市重点基金(No.033801011)资助~~

摘　　要：肿瘤干细胞理论认为只有存在于肿瘤中的少量干细胞性质的细胞群体对肿瘤发生和发展起着决定作用,肿瘤是由干细胞突变积累而形成的无限增殖的异常组织,这一理论的提出使人们对肿瘤发生机制的认识上升到了一个新的高度,也引起了研究者的广泛关注;肝癌是我国常见的恶性肿瘤之一,我国肝癌死亡率居世界之首,目前对肝癌的研究是我国恶性肿瘤防治的重点工作,现对当前肿瘤干细胞与肝癌肿瘤干细胞相关方面的最新研究进展作一概述。According to the tumor stem cell theory, a small portion of cell population that has the stem cell characters plays a dominant role in the tumor generating and developing process. Tumor is an abnormal tissue which have infinite proliferation potential and come into being because of the accumulation of stem cell mutations. This theory brought up the acknowledge of tumor pathogenesis to a higher degree, thus attracted great attention of researchers. Hepatocarcinoma is a common malignant tumor in China, the mortality rate of which is the highest in the world, and its research work is of great importance in our fight against malignant tumor. This paper focuses on the current academic work both in cancer stem cells and its correlated aspects of the hepatocarcinoma stem cells.

关 键 词：肿瘤 干细胞 肿瘤干细胞 肝癌 

分 类 号：R735.7[医药卫生—肿瘤]