镉对姐妹染色单体交换的影响  

THE EFFECT OF CdCl 2 ON SISTER CHROMATID EXCHANGE

作　　者：仪慧兰[1,2] 杨其伟[1,2] 

机构地区：[1]山西大学生命科学系 [2]天津师范大学生物系

出　　处：《山西大学学报（自然科学版）》1996年第4期435-439,共5页Journal of Shanxi University(Natural Science Edition)

摘　　要：以大麦为材料，应用姐妹染色单体分染（ＳＣＤ）技术检测氯化镉溶液对ＤＮＡ的损伤，发现即使镉浓度较低时实验组的姐妹染色单体交换（ＳＣＥ）频率仍显著高于对照。氯化镉溶液处理还影响大麦幼苗的生长分裂，实验组的主胚根及侧根长度、苗高、根系体积均比对照组低，且随着镉浓度的提高抑制效应增强。当镉浓度提高时，大麦胚乳淀粉酶活力及根尖细胞有丝分裂指数均呈下降趋势。因此，镉对生物体的毒害是多方面的。The effect of CdCl 2 solution on sister chromatid exchange (SCE) and growth in seedlings of Hordeum vulgare were studied. It caused SCE frequency increased significantly but the rate of growth inhibited. CdCl 2 could inhibit the activity of amylase. The effect of CdCl 2 solution depended on its concentration. The higher the treated concentration is, the more the degree of inhibition is. Our results showed that CdCl 2 was genotoxic and cytotoxic.

关 键 词：大麦 淀粉酶活力 SCD SCE 镉 DNA损伤 毒理学 

分 类 号：R994.6[医药卫生—毒理学] R995[医药卫生—药学]