乘子法测定复方替硝唑含漱液中二组分的含量  

Simultaneous spectrophotometric determtination of two components in compound tinidazole gargles by multiplication factor method

作　　者：魏得良[1] 黄志红[1] 郭皖北[1] 周明达[2] 王曼娟[2] 刘建华[2] 

机构地区：[1]湘南学院化学与生命科学系,湖南郴州423000 [2]中南大学化学化工学院,湖南长沙410078

出　　处：《中国医院药学杂志》2007年第2期213-215,共3页Chinese Journal of Hospital Pharmacy

基　　金：湖南省教育厅资助项目(编号:05C630)

摘　　要：目的:用乘子法同时测定复方替硝唑含漱液中二组分的含量。方法:用乘子法的原理和计算步骤处理多波长吸收度数据。结果:模拟样品中醋酸氯已定、替硝唑的平均回收率分别为99.75%,100.17%,RSD分别为0.73%,0.42%(n=10),对3个批号实际样品的测定结果与标准方法吻合。结论:与标准方法相比,该方法具有简便、快速、易于实现自动分析的优点。OBJECTIVE To two components in compound tinidazole gargles by multiplication factor method. METHODS The basic principle and computing of multiplication factor method applied to multicomponent analysis. RESULTS The average recovery of chlorhexidine acetate and tinidazole in simulated samples was 99. 75 %, 100.17%, and relative standard deviations for them was 0.73%,0.42% respectively （n = 10）. CONCLUSION The results of determination for three batches of actual samples were agreed with those by standard method.

关 键 词：乘子法 分光光度法 复方替硝唑含漱液 醋酸氯已定 替硝唑 

分 类 号：R927.2[医药卫生—药学]