大白鼠乳腺药物致癌的傅里叶红外光谱研究  

Research in FTIR of the White Mice′s Malignant Mammary Tissue with DMBA Injected into

作　　者：张晓冬[1] 刘素芳[2] 付涛[2] 葛向红[3] 潘聪[4] 

机构地区：[1]郑州轻工业学院技术物理系 [2]郑州铁路职业技术学院信息工程系 [3]中原工学院数理系 [4]河南省实验中学

出　　处：《激光与红外》2007年第3期244-247,共4页Laser & Infrared

摘　　要：运用傅里叶变换红外光谱技术对二甲基苯蒽(DMBA)药物致乳腺癌的大白鼠的正常、增生和癌变组织进行了检测。其分析结果表明:大白鼠乳腺正常与癌变组织的红外光谱存在着明显差异。某些特征谱带(如:1745cm-1,1378cm-1,1465cm-1,970cm-1)发生频移,谱带强度发生改变。探讨这些差异为医生进一步研究人乳腺癌变的机理提供了一些依据。Fourier transform infrared spectroscopy technology was applied to measure the normal ,hyperplastic, malignant mammary tissue of albino rat which DMBA was injected into. The analytic results indicate： there are distinct difference between FTIR of the normal mammary tissue and its malignant mammary tissue. Some characteristic spectrums are shifted （ for example： 1745cm^-1 , 1378cm^-1 , 1465cm^-1 , 970cm^-1 ）, and the intensity of them have changed. Discussing the difference can provide doctor with some gist of researching the reason in human＇s malignant mammary tissue.

关 键 词：大白鼠 乳腺癌组织 傅里叶变换红外光谱 

分 类 号：R73-3[医药卫生—肿瘤] Q95-33[医药卫生—临床医学]