TACE、PEI、PVC三介入联合治疗中晚期肝癌  

Combined Three Intervened Treatment of TACE,PEI And PVC in Advanced Liver Cancer

作　　者：黄平[1] 徐华[1] 刘建辉[1] 吴建兵[1] 李凌[1] 郭武华[1] 魏建平[1] 刘安文[1] 兰琼玉[1] 

机构地区：[1]南昌大学第二附属医院肿瘤科,南昌330006

出　　处：《江西医学院学报》2007年第1期44-46,50,共4页Acta Academiae Medicinae Jiangxi

基　　金：江西省卫生厅资助课题(030077)

摘　　要：目的分析TACE、PEI、PVC三介入联合治疗中晚期原发性肝癌的临床疗效。方法将晚期原发性肝癌60例,分为两组进行治疗:经导管肝动脉栓塞化疗(TACE)组30例(对照组);TACE联合CT引导下无水酒精注射及/或门静脉化疗,即三介入联合治疗组30例(联合治疗组)。观察两组间的生存率及门脉癌栓的消失率。结果对照组6、12、18、24个月生存率分别为56.7%(17/30)、40%(12/30)、20%(6/30)、6.7%(2/30),门脉癌栓消失率43.75%(7/16)。而治疗组6、12、18、24个月生存率分别为76.7%(23/30)、56.7%(17/30)、36.7%(11/30)、16.7%(5/30),门脉癌栓消失率为64.7%(11/17)。两组间生存率及门脉癌栓消失率均有统计学意义(P<0.05)。结论三介入联合治疗优于单纯栓塞化疗。Objective To explore the clinical efficacies of TACE,PEI,PVC,for advanced Liver cancer. Methods Sixty cases of advanced hepatic cancer were divided into two groups. Thirty cases were treated with TACE（control group） and other 30 were with combined ATCE,PEI. and PVC（treatment group）. The two groups were compared for survival rate and disappearance rate of portal vein thrombosis. Results the 6,12,18 and 24 mouths survival rate and disappearance rate of portal vein thrombosis of the control group were 56.7% （17/30） ,40% （12/30） ,20% （6/ 30） ,6.7 % （2/30） ,and 43.75 % （7/16）, respectively; meanwhile those of the treatment group were 76.7%（23/30）,56.7%（17/30）,36. 7%（11/30）,16.7%（5/30）,and 64. 7% （11/17）. The outcomes were significantly different in the two groups in survival rate and disappearance rate of portal vein thrombosis（P〈0.05）. Conclusion Three combined treatment is more effective than the simple TACE treatment.

关 键 词：肝肿瘤 药物疗法 经皮穿刺门静脉插管 化学栓塞 无水乙醇 

分 类 号：R735.7[医药卫生—肿瘤]