Relationship between event-related potential P300 and first episode schizophrenia  

作　　者：CHEN Xing-shi LU Ying-zhi WANG Ji-jun WANG Hong-xing ZHANG Ming-dao LOU Fei-yin CHEN Chong 

机构地区：[1]Department Of Electrophysiology Shanghai Mental Health Center, Shanghai 200030,China [2]Depantment of Psychiatry, Fifth People＇s Hospital, Zibo 255120,Shandong Province, China [3]Department of Electronic EphalographySource Imaging, Shanghai Mental Health Center, Shanghai 200030,China

出　　处：《Chinese Medical Journal》2007年第4期339-341,共3页中华医学杂志（英文版）

基　　金：the Foundation of the Municipal Committee of Shanghai Science and Technology (No.054119534);the National Natural Science Foundation of China (No. 30470626)

摘　　要：Although P300 abnormalities of event-related .potentials （ERPs） are consistently reported among schizophrenic patients as being the most compelling indices of their brain dysfunction, whether they are trait markers or state markers of schizophrenia remains in controversy. To shed a light on this point, we made a longitudinal study of P300 among first episode schizophrenic patients, from no medication until the patients had been medicated for 12 weeks.Although P300 abnormalities of event-related .potentials （ERPs） are consistently reported among schizophrenic patients as being the most compelling indices of their brain dysfunction, whether they are trait markers or state markers of schizophrenia remains in controversy. To shed a light on this point, we made a longitudinal study of P300 among first episode schizophrenic patients, from no medication until the patients had been medicated for 12 weeks.

关 键 词：SCHIZOPHRENIA event-relatedpotentials  P300 memory disorders 

分 类 号：R749.3[医药卫生—神经病学与精神病学]