胃食管反流病患者体表胃电节律的变化规律  

Measurements of surface electrogastrography in patients with gastroesophageal reflux disease

作　　者：孟欣颖[1] 刘红[2] 徐昌青[2] 王义国[2] 王文奇[2] 

机构地区：[1]首都医科大学附属北京友谊医院消化内科,100050 [2]山东省千佛山医院消化内科

出　　处：《中国医师进修杂志（内科版）》2007年第3期20-22,共3页Chinese Journal of Postgraduates of Medicine

摘　　要：目的观察胃食管反流病（GERD）患者的体表胃电节律变化规律及其与患者症状间的关系。方法采用PCPolyg。印hHR双电极胃电记录仪记录25例GERD患者（GERD组）和12例健康人（对照组）的餐前和餐后胃电正常节律的百分比、胃动过缓的百分比、胃动过速的百分比、主频率（DF）、餐后与餐前主功率之比（PR）、DF不稳定系数（DFIC），以及不同症状积分的GERD患者正常节律的百分比、DF、DFIC。结果GERD组患者餐前、餐后胃电正常节律的百分比、DF低于对照组，胃动过缓的百分比、胃动过速的百分比、DFIC均高于对照组，差异有统计学意义。GERD组患者餐前胃电正常节律的百分比、DF低于餐后，而胃动过缓的百分比、DFIC高于餐后，差异有统计学意义。不同症状积分的GERD组患者餐前、餐后胃电节律参数与对照组相比差异均有统计学意义，但各积分组间胃电节律参数差异无统计学意义。结论GERD患者存在胃电生理活动的异常，这种异常可能是GERD的发病机制之一。Objective To study the surface electrogastrography in patients with gastroesophageal reflux disease（GERD）. Methods Electrogastrogram was recorded in 25 patients with GERD （GERD group） and 12 health people （control group） by PC Polygraph HR bipolar electrographic recorder. Patients were also classified into 3 groups according to symptomatic scores. Percentage of normal, percentage of tachygastria, percentage of bradygastria, and dominant frequency（DF）, power ratio（ PR）, DF instable coefficient（DFIC） were analyzed in different-groups. Results Preprandial and postprandial percentage of normal, DF in GERD group were significantly lower than those in control group, while percentage of bradygastria, percentage of tachygastria, DFIC were higher than those in control group. In GERD group, preprandial percentage of normal, DF were lower than tbose in postprandial, and preprandial percentage of bradygastria, DFIC were higher than those in postprandial. The preprandial and postprandial parameters had no significant difference in GERD group with different symptomatic scores. Conclusions Abnormalities in electrogastrogram seem to be one of the pathogenesis of GERD. Surface electrogastrography might be a good method to detect these abnormalities.

关 键 词：胃食管反流病 胃电图 动力 

分 类 号：R57[医药卫生—消化系统]