中药超微粉对早期断奶仔猪白细胞分类和抗氧化功能的影响  

Effects of Chinese Herbal Ultra-Fine Powder as Dietary Additive on Blood Total and Differential Counts of Leucocytes and Serum Anti-oxidative Status in Early-weaned Piglets

作　　者：孔祥峰[1] 刘合军[2] 尹富贵[2] 印遇龙[1] 李铁军[2] 黄瑞林[2] 

机构地区：[1]南昌大学食品工程系,南昌330047 [2]中国科学院亚热带农业生态研究所,长沙410125

出　　处：《天然产物研究与开发》2007年第1期44-47,54,共5页Natural Product Research and Development

基　　金：中国科学院知识创新工程重要方向项目(KSCXZ-SW-323);国家973项目(2004CB117502);国家自然科学基金项目(30671517;30528006)

摘　　要：为了研制高效、安全、无污染的抗生素替代物作为断奶仔猪饲料添加剂,本研究观察了中药超微粉对21日龄断奶仔猪外周血白细胞分类和血清抗氧化功能的影响。结果表明,D7时,超微粉组MDA含量显著小于抗生素组和对照组(P<0.05),NO含量显著小于对照组(P<0.05);D14时,超微粉组NO含量显著大于抗生素组和对照组(P<0.05);D28时,超微粉组NEU计数和百分率及MON百分率均显著小于、LYM百分率显著大于对照组(P<0.05),N/L小于抗生素组(P>0.05)、显著小于对照组(P<0.05),SOD活性显著大于抗生素组和对照组(P<0.05),GSH活性显著大于对照组(P<0.05)。上述指标的变化,与该超微粉对断奶仔猪的防病促生长作用有一定联系。The experiment was conducted to determine the effects of Chinese herbal ultra-fine powder with average granule diameter of 30 μm as dietary additive on blood total and differential counts of leucocytes and serum anti-oxidative status in piglets weaned at 21 day old in order to study and develop a novel antibiotic candidate with strong efficacy and perfect safety. The data showed that the ultra-fine powder decreased the content of MDA compared with the other two groups （ P 〈 0.05 ）, and of NO compared with that of the supplement-free group （ P 〈 0.05 ） on day 7 after the initiation of supplement. On day 14,the content of NO in the power group was higher than that of the other two groups （ P 〈 0.05 ）. On day 28 ,the powder decreased the numbers of NEU and ratio of NEU and MON （ P 〈 0.05 ）, and increased the ratio of LYM compared with the supplement-free groups （ P 〈 0.05 ） ; the power decreased the N-L ratio compared with the supplement-free （P 〉 0.05 ） and colistin groups （P 〈0.05 ） and increased the activity of SOD compared with the other two groups （ P 〈 0.05 ） and of GSH compared with the supplement-free group （ P 〈 0.05 ）. These results suggested that the regulation actions of the Chinese herbal ultra-fine powder to the above-mentioned parameters might be contributed to its functions of preventing disease and promoting growth to the early-weaned piglets.

关 键 词：中药超微粉 早期断奶仔猪 白细胞分类 抗氧化功能 

分 类 号：R285[医药卫生—中药学] S853.74[医药卫生—中医学]