肝苏颗粒治疗非酒精性脂肪性肝炎临床观察  

Clinical Observation of Gansu Granule in the Treatment of Non-alcoholic Steatohepatitis

作　　者：张长法[1] 李子贺[1] 潘雪飞[1] 薛博瑜[2] 金小晶[3] 

机构地区：[1]解放军第454医院,南京210002 [2]南京中医药大学 [3]南京市中医院

出　　处：《药物流行病学杂志》2007年第1期5-7,共3页Chinese Journal of Pharmacoepidemiology

摘　　要：目的:探讨肝苏颗粒治疗非酒精性脂肪性肝炎的疗效。方法:对169例非酒精性脂肪性肝炎随机分为两组,治疗组用肝苏颗粒,对照组用熊去氧胆酸和复方益肝灵片。观察两组治疗前后的症状、体重、生化指标ALT、AST、γ-GT、TC、TG、GS的变化。结果:治疗后治疗组降低体重、ALT、AST、γ-GT、GS恢复,显效率、总有效率优于对照组(P<0．05或P<0．01),TG、TC两组比较P>0．05,但治疗前后比较P<0．05。结论:肝苏颗粒治疗非酒精性肝炎疗效明显,对改善脂质代谢、下调血糖、下降体重,均有较好的作用。Objective： To explore the effect of gansu granule in the treatment of non-alcoholic steatohepatitis. Method： 169 patients with non-alcoholic steatohepatitis were randomly divided into two groups ： treatment group （ n = 85 ） treated with gansu granule and eontroUed group （n = 84） treated with ursodeoxyeholie acid （UDCA） and compound yiganling tablet. The variations of symptom, weight, and blochemieal index; alanin aminotransferase （ALT）, aspartate aminotransferase （AST）, r-glutamyhransferase （r-GT）, totaleholesterol （ TC ）, triglyeeride （ TG ） , blood-glucose （ GS ） for each group before and after the treatment were observed. Result： After the treatment, their body weights decreased and the biochemical index （ALT, AST, r-GT, GS） recovered in the treatment group and the prominent effective ratio and total effective ratio were better than those of the controlled group（ P 〈 0.05 or P 〈 0.01 ）. TG and TC of the treatment group, compared with those of the controlled group, was not significant （P 〉0.05）, but before the treatment they were significant（ P 〉 0, 05 ）, Conclusion： Result： Conclusion： Gansu granule has its curative effect on the patients with non-alcoholic steatohepatitis, and it is valid in improving lipid metabolism and decreasing blood sugar and weight.

关 键 词：肝炎 脂肪性 非酒性 肝苏颗粒 

分 类 号：R575.1[医药卫生—消化系统]