右旋糖酐20葡萄糖注射液细菌内毒素定量检测法研究  

Study on Determination of Bacterial Endotoxin of Dextran 20 Glucose for Injection

作　　者：徐道华[1] 周晨慧[1] 潘正兴[2] 唐继坤[2] 

机构地区：[1]广东医学院药理教研室,广东湛江524023 [2]贵州省药品检验所

出　　处：《中国药师》2007年第3期267-268,共2页China Pharmacist

基　　金：国家药典委员会资助课题[药典业发(2001)第493号]

摘　　要：目的:建立右旋糖酐20葡萄糖注射液细茵内毒素定量检测方法。方法:采用稀释法排除右旋糖酐20葡萄糖注射液对细茵内毒素含量测定的干扰作用。结果:将右旋糖酐20葡萄糖注射液稀释4倍,可排除其对细茵内毒素含量测定的干扰作用。结论:采用细菌内毒素定量检测法检测右旋糖酐20葡萄糖注射液中的细菌内毒素含量是可行的。Objective： To establish a method for determination of bacterial endotoxin of dextran 20 glucose for injection. Method： Dilution method was used to exclude the interference of dextran 20 glucose for injection to the determination of bacterial endotoxin. Resuit： The dextran 20 glucose for injection did not interfere the determination of bacterial endotoxin when they were diluted 4 times. Conclusion： The determination of bacterial endotoxin may be used to dextran 20 glucose for injection.

关 键 词：右旋糖酐20葡萄糖注射液 细菌内毒素 干扰试验 

分 类 号：R927.12[医药卫生—药学]