45例骨转移疼痛不同分割剂量放疗疗效分析  

Radiotherapy with Different Fractionated Dose for 45 Cases with Malignant Bone Metastatic Pain

作　　者：梁晓东[1] 陈卫军[1] 贡强君 刘艳梅[1] 应申鹏 

机构地区：[1]台州市中心医院,浙江台州318000

出　　处：《肿瘤学杂志》2007年第1期62-63,共2页Journal of Chinese Oncology

摘　　要：[目的]探讨不同分割剂量放疗对骨转移癌止痛的疗效。[方法]45例骨转移癌病人采用三种不同分割剂量放疗,分别为DT40Gy/(20F·4w)、DT30Gy/(10F·2w)和DT20Gy/(5F·1w)。[结果]患者止痛有效率为88.89%(40/45),其中25例获得完全缓解。DT40Gy/(20F·4w)组、DT30Gy/(10F·2w)组及DT20Gy/(5F·1w)组的CR率分别为63.64%、57.14%、33.33%;PR率分别为36.36%、32.14%和33.33%,差异均无显著性(P>0.05)。[结论]不同分割剂量放疗对骨转移癌疼痛的缓解程度无影响。[Purpose] To evaluate the effect of pain control with different fractionated dose of radiotherapy in bone metastases from malignancies. [Methods] Forty-five cases with bone metastases received 3 fractionation schedules of radiotherapy： Group 1, 40Gy/20 fractions in 4 weeks; Group 2, 30Gy/10 fractions in 2 weeks and group 3, 20Gy/5 fractions in one week. [ Results ] Overall pain relief rate was 88.89%（40/45）, with complete relief （CR） in 25 cases. The CR rate in group 1,2 and 3 was 63.64%, 57.14%, 33.33% respectively; partial relief （PR） rate was 36.36%,32.14%,33.33% respectively, with no significant difference. [Conclusion] Different fractionated dose of radiotherapy have no influence on pain relief in bone metastases.

关 键 词：骨肿瘤 肿瘤转移 疼痛 放射疗法 放射治疗剂量 

分 类 号：R738.1[医药卫生—肿瘤]