金双歧联合思密达治疗肝源性腹泻33例(英文)  

Golden Bifid Combined with Smecta in Treatment of the Hepatogenous Diarrhea:a Report of 33 Cases

作　　者：瞿章书[1] 汤丽娟[1] 张炜[1] 徐小平[1] 

机构地区：[1]湖南省湘西自治州人民医院(吉首大学第一附属医院)传染科,吉首416000

出　　处：《现代生物医学进展》2007年第2期251-252,共2页Progress in Modern Biomedicine

摘　　要：目的:研究金双歧联合思密达治疗肝源性腹泻的疗效。方法:将66例肝源性腹泻的病人分为两组,治疗组及对照组各33例。两组均给予适当休息、合理饮食,积极护肝及对症支持等综合治疗;在此基础上,治疗组使用金双歧(2．0g,每日三次)联合思密达(3．0g,每日三次)治疗;对照组口服左氧氟沙星(0．2g,每日两次)治疗。疗程均为7天～14天。疗效判断标准:①显效:腹泻消失,大便成形,每日一次;②有效:腹泻次数明显减少或大便基本成形;③无效:症状无改善或大便次数增多。以显效和有效计算总有效率。结果:治疗组显效13例,有效17例,总有效率90．9%;对照组显效10例,有效6例,总有效率48．5%。两组疗效对比差异有统计学意义(x2=15．45,P＜0．001)。结论:金双歧联合思密达治疗肝源性腹泻疗效显著,值得临床推广应用。Objective： To explore the therapeutic effect of Golden bifid combined with smecta for the patients with hepatogenous diarrhea （HD）. Methods： 66 patients with HD were randomly divided into treatment group （n=33） and control group （n=33）.On the basis of protecting the liver and the complex treatment, the treatment group was given Golden bifid （2.0g, three times a day） combined with smecta （3.0g,three times a day）, and the control group was given levofloxacin （0.2g, twice a day）. The efficacy standards were as follows： ① remarkable effect： diarrhea disappeared, stool was shaped, feces daily; ② effective： the number of diarrhea significantly reduced or stool almost formed;③　Null and void： symptoms were not improved or frequent stools, the total efficiency （remarkable effect and effective） of two groups was calculated. Results： The total effective rate of treatment group was 90.9% while that of the control group was 48.5%. There were statistically significant differences between the two groups （x^2=4.19,P〈0.01）. Conclusion： The clinical therapeutic effect of Golden bifid combined with smecta for the patients with hepatogenous diarrhea is remarkable,which is worth spreading in the clinical application.

关 键 词：金双歧 思密达 肝源性腹泻 

分 类 号：R574.62[医药卫生—消化系统] R575.2[医药卫生—内科学]