上尿路上皮癌术后发生膀胱癌的危险因素分析  

Risk factors of the occurrence bladder tumor after resection of upper urinary tract epithelial carcinoma

作　　者：董涛[1] 董胜国[1] 付伟伟[1] 

机构地区：[1]青岛大学医学院附属医院,山东青岛266003

出　　处：《基层医学论坛》2007年第4期298-299,共2页The Medical Forum

摘　　要：目的探讨上尿路上皮癌术后膀胱癌的发生规律及对预后的影响。方法回顾93例上尿路上皮癌病例的临床与病理特点,对预后以及术后发生膀胱癌情况分别做Kaplan-Meier曲线单因素分析,并行Log-rank检验,再应用Cox比例风险模型分析。结果93例患者接受根治手术后发生膀胱癌者28例,占30.1%。有无多部位生长和有无同发膀胱癌对术后发生膀胱癌有显著影响,其相对危险度分别为1.894和4.483,相关系数小;与术后存活率显著相关的因素有3个,肿瘤数目、分期、有无同发膀胱癌,相对危险度分别为2.822、2.197和1.808,相关系数小。结论肿瘤数目、有无多部位生长和有无同发膀胱癌为术后发生膀胱癌的危险因素;肿瘤数目、分期、有无同发膀胱癌对存活率有显著影响。Objective To study the clinic features and prognosis of intravesical occurrence after resection of upper urinary tract epithelial carcinoma. Methods The clinicopathological features of 93 cases of urinary tract epithelial carcinoma were retrospectively studied. Cox＇s analysis, Kaplan Meier function and log-rank test were used to assess the influence of the intravesical occurrence of the cancer. Results There were 28 cases with intravesical occurrence of the 93 cases after kidney ureter and partial bladder resection. The muhiplace growth of the primary cancer and concurrent bladder cancer were significantly related to the occurrence of intravesical occurrence of the cancer after surgical management. Their relative risk were 1.894 and 4.483, with the coefficient correlation being low. The number and the stage of the primary cancer, with concurrent bladder cancer were significant factors for prognosis, with a hazard index of 2.822,2.197 and 1.808 respectively. The coefficient correlation was low, Conclusion The relative risk value and hazard index of the factors above can be estimated to evaluate the prognosis including recurrence of bladder carcinoma and survival rate.

关 键 词：尿路 上皮 膀胱 癌 预后 

分 类 号：R737.1[医药卫生—肿瘤]