江苏省大丰市胃癌危险因素病例对照研究  

A Case-control Study on Risk Factors of Stomach Cancer in Dafeng County,Jiangsu Province

作　　者：刘爱民[1] 赵金扣[1] 武鸣[2] 圣龙贵[3] 袁峰[3] 陈娟[3] 顾小平[3] 仇磊[3] 王建军[3] 杨婕[2] 周金意[2] 张作风 

机构地区：[1]南京医科大学,江苏南京210029 [2]江苏省疾病预防控制中心,江苏南京210009 [3]江苏省大丰市疾病预防控制中心,江苏大丰224100 [4]美国加州洛杉矶大学公共卫生院,900951772

出　　处：《中国肿瘤》2007年第3期152-154,共3页China Cancer

摘　　要：[目的]探讨大丰市与胃癌发病有关的危险因素。[方法]选择大丰市进行以人群为基础的胃癌1∶1配对病例对照研究,共调查胃癌病例和对照各649例,配成对数649对。结果采用单因素及多因素条件Logistic回归方法进行分析。[结果]A型血(OR=3.127,95%CI:1.488～6.571),进食速度快(OR=3.587,95%CI:2.570～5.006),喜食咸(OR=2.703,95%CI:1.261～5.794)或烫(OR=3.445,95%CI:2.526～4.697)食品,性格忧郁(OR=2.512,95%CI:1.333～6.819)等为大丰市胃癌发病的主要危险因素,而粮食储具常清洗翻晒(OR=0.054,95%CI:0.004～0.815),喜食大蒜(OR=0.337,95%CI:0.048～0.651),常食用新鲜蔬菜(OR=0.488,95%CI:0.274～0.869)等则为其保护因素。[结论]应当通过教育居民改变不良的生活饮食习惯、注意心理精神卫生以降低胃癌发病危险性。[Purpose] To explore the risk factor of stomach cancer in Dafeng city.[Methods] A population-based,1∶1 matched case-control study was conducted among 649 cases and 649 controls in Dafeng County,Univariate and multivariate conditional logistic regression analyses were used to identify risk factors of stomach cancer.[Results] Blood-type A（OR=3.127,95% CI：1.488～6.57）,fast eating（OR=3.587,95%CI：2.570～5.006）,heavy salt consumption（OR=2.703,95%CI：1.261～5.794）,heavy hot papper consumption（OR=3.445,95%CI：2.526～4.697）,and depressed character （OR=2.512,95%CI：1.333～6.819） significantly increased the risk of developing stomach cancer, while using clearly grain container （OR=0.0536,95%CI：0.004～0.815, raw garlic （OR=0.337,95%CI：0.048～0.651）, fresh vegetable （OR=0.488,95%CI：0.274～0.869） were protective factors for the stomach cancer. [Conclusion] Healthy lifestyle and dietary pattern, and healthy psychological status could reduce the risk of stomach cancer.

关 键 词：胃肿瘤 危险因素 病例对照研究 LOGISTIC回归分析 

分 类 号：R735.2[医药卫生—肿瘤]