基因芯片技术研究进展  

Research Progress of Gene Chip Technology

作　　者：王洪水[1] 侯相山[1] 

机构地区：[1]东营职业学院,山东东营257091

出　　处：《安徽农业科学》2007年第8期2241-2243,2245,共4页Journal of Anhui Agricultural Sciences

摘　　要：主要就基因芯片的概念、技术原理、分类、主要技术流程、应用及其存在的问题和应用前景作了综述。Gene chip was a newly developed technology in recent years. Light-directed in situ oligonucleotide synthesis or microarray printing technique was adopted in its basic process in order to generate arrays of large amounts of probes on the surface of small substrates such as silicon chips, which was hybridized to the amplified and labeled samples. After scanning and analyzing, the signals provided hereditary information on the samples. This technology could not only be used to qualitative analysis or quantitative analysis of hereditary information, but also could be used to genome study and gene diagnosis. Concept, technique mechanism, category, main technique process, applications, existent problems and its application foreground of gene chip were summarized in this review.

关 键 词：基因芯片 基因组研究 基因诊断 技术流程 

分 类 号：Q78[生物学—分子生物学]