复发性翼状胬肉不同术式的疗效研究  

A comparison of different operative procedures for recurrent pterygium.

作　　者：袁军[1] 叶卫军[2] 张娇[1] 汪晓玲[1] 孙权蓉[1] 

机构地区：[1]广元市第二人民医院眼科,四川广元628017 [2]绵竹市人民医院眼科,四川绵竹618200

出　　处：《临床和实验医学杂志》2007年第3期43-44,共2页Journal of Clinical and Experimental Medicine

摘　　要：目的比较自体角膜缘干细胞移植术、丝裂霉素C联合自体角膜缘干细胞移植术、丝裂霉素C联合带蒂结膜瓣转移术的临床疗效。方法98眼97例复发性翼状胬肉患者随机分成A、B、C三组，A组34眼行自体角膜缘干细胞移植术，B组38眼行丝裂霉素C联合自体角膜缘干细胞移植术，C组26眼行丝裂霉素C联合带蒂结膜瓣转移术，随访8—36个月，比较各组患者术后翼状胬肉复发情况。结果A组34眼中有14眼复发，复发率41．2％；B组38眼中有5眼复发，复发率13．2％；C组26眼中有4眼复发，复发率14．8％。A组与B组比较X^2=5．81，P〈0．05，A组与C组比较X^2=4．67，P〈0．05，B组与C组比较X^2=0．02，P〉0．1。结论丝裂霉素C联合自体角膜缘干细胞移植术、丝裂霉素C联合带蒂结膜瓣转移术是治疗复发性翼状胬肉较理想的手术方法。Objective To investigate the therapeutic effect of corneal limbal stem cells autografting, mitomycin C plus corneal limbal stem cells autografting and mitomycin C plus transference of pedicled conjunctival flap. Methods 98 eyes of 97 patients with recurrent pterygium were randomized into three groups ： corneal limbal stem cells autografting （ groups A, 34 eyes）, mitomycin C plus corneal limbal stem cells autografting （groups B, 38 eyes） and mitomycin C plus transference of pedicled conjunctival flap （groups C, 26 eyes）. Patients were followed up for 8- 36 mouths, recurrence rates of the three groups were compared. Results The recurrent rate was 41.2% in group A （ 14/of 34 eyes ）, 13.2% in group B, （5/38 eyes）, 14.8% in group C （4/26 eyes ）. The differences were significant between group A and group B （X^2 =5.81, P 〈0. 05 ）, between group A and group C （ X^2 = 4.67, P 〈 0. 05 ）, but there were no significant differences between group B and group C （ X^2 = 0, 02, P 〉 0. 1 ）. Conclusion Mitomycin C plus corneal limbal stem cells autografting and mitomycin C plus transference of pedicled conjunctival flap are two ideal therapeutic methods for recurrent pterygium.

关 键 词：复发性翼状胬肉 丝裂霉素C 角膜缘干细胞移植 带蒂结膜瓣转移术 

分 类 号：R779.6[医药卫生—眼科]