Synthesis of novel chiral stationary phases for high-performance liquid chromatography  

作　　者：Xu Lin Tan Shi Cong Hou Qing Hua Bian Min Wang 

机构地区：[1]College of Science, China Agricultural University, Beijing 100094, China

出　　处：《Chinese Chemical Letters》2007年第4期461-464,共4页中国化学快报（英文版）

基　　金：the National Natural Science Foundation of China （No. 20472111） is gratefully acknowledged.

摘　　要：Three novel chiral selectors 4a-c were synthesized from （S）-amino acids and （R）-1-phenyl-2-（4-methylphenyl）ethylamine. 4a-c were connected to 3-aminopropylsilanized silica gel to be used as the chiral stationary phase for HPLC. Five amino acid derivatives and two pyrethroid insecticides were fairly resolved on these three new chiral stationary phases under normal phase condition.Three novel chiral selectors 4a-c were synthesized from （S）-amino acids and （R）-1-phenyl-2-（4-methylphenyl）ethylamine. 4a-c were connected to 3-aminopropylsilanized silica gel to be used as the chiral stationary phase for HPLC. Five amino acid derivatives and two pyrethroid insecticides were fairly resolved on these three new chiral stationary phases under normal phase condition.

关 键 词：ENANTIOSEPARATION Chiral stationary phase Amino acid derivatives Pyrethroid insecticides 

分 类 号：O657.72[理学—分析化学]