肾癌及免疫外科治疗69例  

Surgical Therapy and Immunotherapy For Renal Cancer (Report of 69 cases)

作　　者：谭朝晖[1] 李三祥[1] 

机构地区：[1]内蒙古自治区医院泌尿外科,内蒙古呼和浩特010017

出　　处：《内蒙古医学杂志》2007年第2期161-163,共3页Inner Mongolia Medical Journal

摘　　要：目的：探讨肾细胞癌不同外科治疗方法及免疫治疗的临床应用。方法：通过外科手术的方法治疗79例肾细胞癌患者，术后部分患者给予免疫治疗，观察其疗效。结果：65例获6个月～5年随访，1年和3年生存率分别为95．6％和88．3％。保留肾单位手术的病例术后继发性出血1例，经保守治疗后控制；术后漏尿1例，留置双管4周后逐渐好转。平均随访时间19个月，1例患者出现远处转移死亡（双侧肾癌患者），1例术后6个月局部复发者行根治性肾切除，其余病例未发现局部复发和远处转移。术后免疫治疗期间出现一过性发热者15例，轻度恶心者5例，血白细胞减少者1例。结论：外科手术仍是目前治疗肾癌的主要手段。对于无明确远处转移、对侧肾功能正常者，根治性肾切除是标准的术式；直径小于3cm、部位靠近肾表面的小肾癌分别作肾部分切除和肿瘤剜除术，与根治手术的术后生存率相近。免疫治疗可明显提高生存率。objective： To evaluate the clinical application of various surgicaltherapy and immuno therapy in renal cell cancer. Methods： The clinical data of 79 patients with renal cell cancer undergoing surgery and immunotherapy were reviewed and analyzed. Results： Followed up between 6 months and 5 years, the 1 year survival rate and 3 year Survival rate of 65 patients was respectively 95.6 % and 88.3%. After surgery, 1 case complicated with secondary hemorrhage and 1 with urine fistula. Both of them improved with conservated treatment. 1 case died by distant metastasis and 1 occured local recurrence. There were 15 cases with temporary fever, 5 mlid nausea and 1 leucocytopenia during immunotherapy. Conclusion： Surgery is still the major methods in treating renal cancer. Radical nephrectomy is the standard approach forrenal cancer with normal another kidney and without distant metastasis. Part nephrectomy is effective in treating topical small carcinoma. Immunotherapy can markedly improve survical rate.

关 键 词：肾癌 手术 免疫治疗 

分 类 号：R735.2[医药卫生—肿瘤]