子宫外子宫内膜间质肉瘤的临床病理观察  

Clinical Pathology of Extrauterine Endometrial Stromal Sarcoma

作　　者：佟晓 

机构地区：[1]乌海市妇幼保健院病理科,内蒙古乌海016000

出　　处：《内蒙古医学杂志》2007年第2期175-177,F0004,共4页Inner Mongolia Medical Journal

摘　　要：目的:探讨子宫外子宫内膜间质肉瘤(ESS)的临床病理学特点。方法:应用光镜和免疫组化标记对2例子宫外原发性ESS进行回顾性研究。结果:2例子宫外原发性ESS的光镜下组织形态均显示瘤组织由浸润性弥漫性增生的单一性圆形或梭形细胞组成,核分裂数<10个/10HPF,间质小血管丰富,其中1例伴有明确的子宫内膜异位症。免疫组化:肿瘤细胞Vim、CD10、PR、ER均(+),EMA、S-100、LCA均(-)。结论:子宫外原发性ESS非常少见,其形态学和免疫组化表达提示可能起源于子宫内膜异位症,其瘤细胞来自异位子宫内膜间质细胞。Objective：To investigate clinical pathologic features of extrauterine endometrial stromal sarcoma （ESS）. Methods： 2 cases with essential extrauterine ESS were retrospectively analyzed by light microscope and immunohistochemistry. Results： With light microscope, 2 cases with ESS showed invasive and diffuse oncocytes in round or fusiforrn shap, with karyokines is less than 10 per 10HPF, stroma with much small vessels. 1 of 2 cases complicated with endometriosis. With immunohistochemistry, the vim, CD10, PR and ER was positive, but the EMA, S- 100 and LCA was negative in tumors. Conclusion： Extrauterine ESS is infrequent disease. The mophologic and immunohistochemical results indicate the tumor developed from endometriosis and the oncocyte originated from interstitial cell of ectopic endometrium.

关 键 词：子宫内膜间质肉瘤 子宫外 子宫内膜异位症 免疫组化 

分 类 号：R36[医药卫生—病理学] R737.33[医药卫生—基础医学]