胃癌性激素依赖性的研究  

A Study on Sexual Hormone Dependent in Patients with Stomach Cancer.

作　　者：马去非[1] 王金钟[1] 王汉卿 赵全年[1] 李小军[1] 赵俊卿[1] 

机构地区：[1]呼和浩特铁路局中心医院

出　　处：《铁道医学》1996年第6期334-335,T013,共3页Railway Medical Journal

摘　　要：对１００例进展期胃癌临床病理资料及手术标本进行三种性激素受体（ＨＲ）检测，结果表明胃癌在发生率、年龄分布、大体及组织学类型、癌组织ＨＲ状况等方面均存在显著性别差异。推测胃癌临床病理表现的差异是由于体内各种性激素的浓度不同以及癌组织内相应受体的含量不同所致，部分胃癌可能为性激素依赖性（雌激素依赖性或雄激素依赖性），提出对胃癌进行内分泌治疗的可能性。One hundred cases of progressive stomach cancer were studied clinico-pathologically.There were significant differences for the incidence rate,age,macro and micropathological types between male and female patients.Beside,estrogen receptor(ER),progesterone receptor(PR) and androgen receptor(AR) of 100 cases of stomach cancer were measured.ER,PR and AR were found in male and female.It suggested that the differences of clinical and pathological features between men and women were based on the differences in level of the sexual hormones and the relevent receptors in the cancer tissues.Some stomach cancers were sexial hormone dependent (estrogen or androgen hormone dependent).Therefore,it is possible to provide hormone therapy to the patients with stomach cancer.

关 键 词：病理 性别差异 性激素依赖 受体 胃肿瘤 

分 类 号：R735.202[医药卫生—肿瘤] R730.231.4[医药卫生—临床医学]