中西医结合治疗肝郁气滞型功能性消化不良的临床观察  

The Clinic Observed of Combination of Traditional Chinese Medicine with Westen Medicine to Treated the Depression of Liver-Energy Type of Functional Dyspepsia

作　　者：黄学军[1] 龚梅恩[1] 罗仁浩[1] 刘伟[1] 刘月婵[1] 

机构地区：[1]广州医学院第二附属医院,广东广州510260

出　　处：《中国民康医学》2007年第7期307-308,共2页Medical Journal of Chinese People’s Health

摘　　要：目的:探讨抗抑郁和疏肝理气法治疗功能性消化不良(FD)的临床疗效。方法:选择肝郁气滞型FD患者120例,随机分为舍曲林组(A组)、四逆散加味组(B组)和两种方法合用组(C组)各40例,治疗前及治疗6周后各评定一次FD临床症状、汉密尔顿抑郁量表(HAMD)、副反应量表(TESS)。结果:A组FD患者临床症状改善总有效率为82.5%,B组为80.0%,C组为92.5%;A组和B组与C组比较经统计学u检验差异均有显著意义(P<0.05)。三组病人治疗前后HAMD量表评分经t检验均有显著性差异(P<0.01)。不良反应少,复发率低。结论:舍曲林的抗抑郁和四逆散加味的疏肝理气法治疗肝郁气滞型FD的临床疗效显著,联合用药效果更好,不良反应少。Objective： To validate the clinical effectiveness of Antidepressive and disperse the depressed liver - energy and rectify it in the treatment of functional dyspepsia. Methods： A total of one hundred and twenty cases with functional dyspepsia. We are randomly averaged divided into three groups （ n = 40）. Group A with the Sertraline treatment, Group B with the SiNiSan decoction treatment, Group C mixed with the Sertraline and the SiNiSan decoction treatment for 6 weeks. We checked with the FD Clinic Symptom, HAMD and TESS. Results： Group A the Clinic Symptom improved general efficiency is 82.5%. Group B is 80.0%. Group C is 92.5%. Group A and Group B separate compared with Group C. The u test of statistics are shown notability significance（ P 〈 0.05 ）. The test of statistics are shown notability significance（ P 〈 0.01 ） for that the three groups of patients before and after the treatment. Lack of side effect. Low recrudesce rate. Conclusions： Antidepressive drugs of Sertraline and disperse the depressed liver - energyand and rectify it of the SiNiSan decoctionto to treated the depression of liver - energy type of FD. The curative effect are notability. The better effect of united medicine used. Lowness side effect.

关 键 词：功能性消化不良 肝郁气滞 舍曲林 四逆散加味 

分 类 号：R573.9[医药卫生—消化系统]