昆虫乙酰胆碱酯酶基因变异抗药性机制研究  

Advances in studies of acetylcholinesterase gene variation assoiated with insect resistance

作　　者：曲明静[1] 许新军[2] 韩召军[2] 姜晓静[3] 

机构地区：[1]山东省花生研究所,青岛266100 [2]山东出入境检验检疫局动植处,青岛266002 [3]南京农业大学农业部病虫监测与治理重点开放实验室,南京210095

出　　处：《昆虫知识》2007年第2期191-194,共4页Entomological Knowledge

基　　金：粮食丰产科技工程资助项目(2004BA520A15)

摘　　要：有机磷和氨基甲酸酯类杀虫剂的大量使用导致昆虫对其产生抗药性。乙酰胆碱酯酶是昆虫对这类杀虫剂产生抗性的重要的靶标酶,昆虫产生抗药性的重要原因之一,就是因为乙酰胆碱酯酶的基因表达量上升,或基因突变而导致其敏感性下降。文章简要论述昆虫乙酰胆碱酯酶基因发生变异而导致的抗药性,分析了变异对其结构和功能的影响。Intensive use of organophosphate and earbamate insecticides led to development of resistance in many insects. Acetylcholinesterase is an important target enzyme to these insecticides. One of the most important reasons for resistance development is acetylcholinesterase increasing expression or point mutation that makes its insensitivity. Here Acetylcholinesterase gene variation conferring insecticides resistance in the pests is summarized briefly and the effects of acetylcholinesterase mutation on its structure and functions were discussed.

关 键 词：乙酰胆碱酯酶 表达量 点突变 昆虫 

分 类 号：S433[农业科学—农业昆虫与害虫防治]