头颈部非霍奇金淋巴瘤68例临床分析  

A clinical analysis of 68 cases of non-Hodgkin’s lymphoma in head and neck

作　　者：李红[1] 王选琴[2] 李明红[1] 杨桦[1] 镡旭民[1] 

机构地区：[1]第三军医大学新桥医院耳鼻咽喉-头颈外科,重庆400037 [2]重庆医科大学附属儿童医院耳鼻咽喉科,重庆400014

出　　处：《第三军医大学学报》2007年第7期641-642,共2页Journal of Third Military Medical University

摘　　要：目的探讨头颈部非霍奇金淋巴瘤的诊断方法和治疗措施。方法对68例经病理诊断的非霍奇金淋巴瘤,进行临床分期、病理组织类型分类,采用化疗、放疗及部分结合手术等综合治疗42例,单一化疗20例,单一放疗6例。结果68例患者1、3、5年生存率分别为56%,38%,22%,存活患者以早期者占绝大多数,且多为恶性程度较低者,死亡患者中以晚期为多。结论诊断本病需明确非霍奇金淋巴瘤的类型和判定病变累及的部位及范围,对原因不明的颈部肿大淋巴结应反复活检以明确诊断,治疗效果好坏的关键在于选择治疗方案的正确与否,综合治疗是最为有效的治疗手段,预后与组织类型、临床分期有密切关系。Objective To explore the diagnosis and treatment measures of non-Hodgkin＇ s lymphoma （NHL） in head and neck. Methods After pathological diagnosis, clinical staging and the classification of pathological tissue types, 42 cases accepted systematic treatment, 20 cases accepted chemotherapy alone and 6 cases radiotherapy only. Results The survival rates of the 68 patients for 1 year, 3 years, and 5 years were 58% , 38% and 22% respectively. Among the survivals, most were early and low malignant lymphomas while among the dead most were at advanced stage. Conclusion The diagnosis of non-Hodgkin＇ s lymphoma should include the affirmation of lymphoma type and the region and size of pathological insult. Repeated biopsy should be carried out if unexplained lymphadenectasis is present in the neck. Chemotherapy combining with radiotherapy and operation is proved to be the most efficient therapeutic method. The prognosis is closely related with the pathological classification and clinical stage.

关 键 词：非霍奇金淋巴瘤 诊断 治疗 头颈部 

分 类 号：R733.1[医药卫生—肿瘤] R739.91[医药卫生—临床医学]