口腔颌面部恶性黑色素瘤─—预后因素探讨  

Prognostic factors in malignant melanoma of the oral maxillofacial region

作　　者：黄敏娴[1] 高岩[1] 马大权[1] 俞光岩[1] 蔡志刚[1] 

机构地区：[1]北京医科大学附属口腔医学院口腔颌面外科,北京医科大学附属口腔医学院病理科

出　　处：《耳鼻咽喉（头颈外科）》1996年第4期239-242,共4页Chinese Arch Otolaryngology-Head Neck Surg

摘　　要：本文将我科１９６７年７月～１９９３年７月收治４４例口腔颌面部恶性黑色素瘤进行临床与病理分析，探讨影响预后因素。男３１例，女１３例，年龄２５～７８岁，中位数４６岁。颌面部皮肤恶性黑色素瘤５例，口腔粘膜３９例。对４１例行２～３０年随诊，初治病例３５例中２６例（７４．２％）局部复发。全组病例中２４例（５８．５％）区域淋巴结转移，１６例（３９．０％）远处转移，３５例（８５．４％）死亡。其结果说明口腔颌面部恶性黑色素瘤预后与肿瘤部位、肿瘤的临床与病理分型、病变侵袭深度、淋巴结有无转移、治疗方式有关。Abstract Forty-four cases of malignant melanoma of oral andmaxilldacial region were analysed to find out the factors influencing the prognosis. There were 31 males and 13 females rang-ing in age from 25 to 78 years. Among 44 patients,43 were treated by surgery,of which 12 received chemotherapy;1 patient was treated by Chinese traditional medicine because of ex-tensive metastasis of the tumor. 41 patients(93.2%)were followed-up for 2～10 years.Among 44 patients,24 had metastasis(39.0%),35(85.5%)died within 10 years. The re-sults demonstrated that the prognosis of oral and maxillofacial malignant melanoma related closely with tumor size,tumor type(according to clinical and pathological classification ),depth of invasion,regional metastasis and the way of treatment.

关 键 词：口腔颌面部肿瘤 黑色素瘤 预后 

分 类 号：R739.807[医药卫生—肿瘤]