大肠癌癌瘤周边粘膜改变的X线－病理研究（附227处切面的观察）  

Radiological and Pathological Studies of the Mucosa arround the Large Intestinal Carcinoma

作　　者：陈棣华[1] 陈金城[1] 蒋光愉[1] 

机构地区：[1]暨南大学医学院附属医院医学影像科

出　　处：《暨南大学学报（自然科学与医学版）》1996年第2期83-88,共6页Journal of Jinan University(Natural Science & Medicine Edition)

摘　　要：用Ｘ线－病理对照方法，对经手术病理证实，并有较完整Ｘ线资料的１１例大肠癌手术切除标本进行了２２７处切面的观察。结果发现１）癌瘤与周边粘膜的交界面，实际是癌瘤与慢性炎症的交界面；２）Ｘ线表现粘膜皱襞减少及不规则区，病理所见全部是癌组织与炎症组织的交界区；３）Ｘ线显示粘膜皱襞消失区，其病理改变除了粘膜下水肿、腺体腺瘤样增生及腺上皮不典型增生外，在粘膜下层还可以见到少量癌组织，因此在确定癌瘤侵犯范围时应引起注意；４）同时癌瘤近端周边粘膜的重度慢性炎症较远端周边显著，说明在监测大肠癌的发生与发展时，更应注意癌瘤近端周边肠管的Ｘ线病理改变。Using the radiological -- pathological comparision method, 227 cross sections wereexamined from 11 resected specimen of pathologically -- convinced large intestinal carcinoma with complete radiological data. The results showed that 1) Arround carcinoma the intedece between carcinoma and mucosa was actually the interface between carcinoma and chronic inflammation;2) The X--ray manifestaation of mucosal plicae decreasing and irregular area pathologically speaking were completely the junction area of carcinoma and inflammation, 3) Radiological mucosal disappeared area were pathologically submucosal edema, adenomatoid hyperplasia and glandular epithelium atypical hyperplasia, besides, a little carcinama tissue could be seen insubmucosa. So more attentions should be paid to decide the invasive range of the carcinoma,4) Meanwhile, the chronic inflammation in proximal portion of mucosa arround the carinoma was more severer than that of distal portion, so was the glandular epitheliam atypical hyperplasia. When the occurrence and development of large intestinal carcinoma were surveied, it is suggested that more attention should be paid to the radiological and pathological manifestation of the proimal portion of the intestinal mucosa arround the carcinoma.

关 键 词：大肠癌 癌瘤周边粘膜 病理学 结肠双重造影 

分 类 号：R735.34[医药卫生—肿瘤]