结晶纤维素降解酶的研究进展  

Study on the Crystalline Cellulose-degrading Enzyme

作　　者：吴窈画[1] 彭惠[1] 邵蔚蓝[1] 

机构地区：[1]南京师范大学微生物工程重点实验室,江苏南京210097

出　　处：《安徽农业科学》2007年第9期2532-2534,共3页Journal of Anhui Agricultural Sciences

基　　金：江苏省高技术研究项目(BG20050326)

摘　　要：纤维素的结晶区是纤维素酶降解纤维素效率不高的制约因素。在纤维素生物降解的基础上,从产结晶纤维素酶的微生物,酶的作用机理,酶的基因工程与蛋白工程,以及结晶纤维素酶的研究前景等方面对结晶纤维素的降解作了综合评述。Despite its simple chemical composition, cellulose exists in a number of crystalline and amorphous topologies. Its insolubility and heterogeneity makes native cellulose a recalcitrant substrate for enzymatic hydrolysis. On the basis of the hydrolysis of cellulosic biomass, in this review the basic research on crystalline cellulose-degrading enzyme was concemed. Main avicelase-producing organisms were described. A mechanistic model for the action of enzyme complexes on the surface of insoluble substrates,some opportunities of cellulase improvement by means of gene and protein engineering and its biotechnological perspectives were discussed.

关 键 词：结晶纤维素 降解酶 纤维小体 

分 类 号：Q936[生物学—微生物学]