大鼠胃经下肢3个穴位皮下传入神经在脊神经节的重叠分布  

Overlapping Distribution of Subcutaneous Primary Afferents in Nearby Acupoints of Stomach Meridian

作　　者：邓云平[1] 梅斌[1] 茹立强[1] 关新民[1] 

机构地区：[1]同济医科大学基础医学院神经生物学教研室,武汉430030

出　　处：《同济医科大学学报》1996年第3期195-198,202,T251,共5页Acta Universitatis Medicinae Tongji

基　　金：国家攀登计划经络研究课题(NO.930106)

摘　　要：用霍乱毒素B亚单位标记辣根过氧化物酶(CB-HRP)及荧光双标(核黄、快蓝)示踪方法,观察了大鼠足阳明胃经上3个相距较近穴位:伏兔(ST32)、足三里(ST36)和下巨虚(ST39)皮下感觉传入神经在脊神经节的节段性分布.结果:①同一穴区的皮下感觉神经可来自几个不同节段的脊神经节.标记细胞数量呈正态分布.标记的脊神经节细胞主要为中、小型.伏兔穴与T11～L6脊神经节有关,其中LZ、L3标记细胞最多,足三里穴亦与T11～L6有关,以L3标记细胞最多,L2、L4次之;下巨虚穴仅与L2～L5有关,L3、L4标记细胞最多.②同一脊神经节可支配几个穴区皮下组织.3个穴区皮下组织均接受L2～L5脊神经节的支配,其中L3脊神经节是此3个穴区皮下传入神经分布最为密集的节段.③核黄和快蓝逆行荧光双标记研究发现,少数L3、L4脊神经节细胞可分支支配足三里及下巨虚穴区皮下组织.同一经络线上相距较近3个穴位区皮下感觉神经节段性投射的重叠性分布,以及同一脊神经节细胞可分支支配2个不同穴位的现象的证实可为循经感传机制的研究提供一些形态学依据.Using CB - HRP and fluorescein tracing method, we investigated the distribution of subcutaneous primary afferents in "Futu"(ST32), "Zusanli"(ST36) and "Xiajuxu"(ST39) acupoints which belong to the same traditional Chinese meridian——the "Zuyang-ming" Stomach Meridian. The results were as follows; ① Subcutaneous primary sensory afferents in an acupoint could project to several dorsal root ganglia (DRG). Cells labelled in DRG were mainly of small and middle size and they were in normal distribution in number. In "Futu" and "Zusanli" acupoints the subcutaneous afferent nerves projected to T11-L6DRG with a predominant number of labelled neurons in L2,L3 and L3 respectively, while in"Xiajuxu" acupoint the afferent nerves were only related to L2～L5 DRG in which most ofthe labelled neurons were in L3 and L4. ② One DRG could innervate subcutaneous tissues of several acupoints. L3 DRG was the main ganglion which innervated intensely all of the three acupoints studied. ③ Using retrograde fluorescein double-labelling method, we found that a few of DRG neurons at segments L3 and L4 could collaterally innervate subcutaneous tissues of the area of "Zusanli" and "Xiajuxu" acupoints. The overlapping distribution of subcutaneous primary afferents in acupoints of the same meridian with short distance between them may be related to the propagated sensation along the meridian.

关 键 词：胃经 穴位 径路示踪 脊神经节 重叠分布 

分 类 号：R224.2[医药卫生—中医基础理论] R322.85[医药卫生—中医学]