微创穿刺术治疗基底节脑出血的随机对照研究  

Minimally Invasive Paracentesis for Spontaneous Basal Ganglia Hemorrhage:A Randomized Controlled Trial

作　　者：郑兴荣[1] 付耀高[2] 韩秀琴[3] 吴光先 

机构地区：[1]广州增城市新塘医院内科,510300 [2]广州暨南大学附属第一医院神经内科 [3]黑龙江省鸡西市人民医院 [4]江西省信丰县人民医院

出　　处：《岭南急诊医学杂志》2007年第2期104-106,共3页Lingnan Journal of Emergency Medicine

摘　　要：目的:比较微创穿刺血肿粉碎清除术和内科保守方法治疗基底节区脑出血(出血量25～40mL)的临床疗效。方法:随机将74例分入微创穿刺血肿粉碎清除术组(A组)40例和内科保守治疗组(B组)34例进行治疗。评价治疗第14d时两组患者神经功能缺损程度和日常生活活动能力、第90d时改良Rankin量表评分及Barthel指数评分。结果:治疗后第14d时A组斯堪的纳维亚卒中量表评分明显优于B组(P<0.05)。治疗后第90d时微创组改良Rankin量表评分和Barthel指数评分优于内科组(P<0.05),微创组的致残率和明显依赖生存率低于内科组(P<0.05)。结论:与单纯内科保守治疗相比,微创血肿清除术治疗基底节区脑出血(出血量25～40mL),可以明显提高患者的日常生活活动能力,降低致残率和明显依赖生存率,且不增加病死率。Objective： To compare the clinical effect of the minimally invasive paracentesis with conservative medical treatment in treating patients with 25-40 mL spontaneous basal ganglia intracerebral hemorrhage. Methods： 74 patients were randomLy divided into ＂Punctures group＂ （Group A, n=40） and ＂Conservative group＂ （ Group B, n=34）. The Scandinavian Stroke Scale （SSS） score in the 14^Th day, modified Rankin Scale （MRS） score in the 14^Thand 90^Th day, Barthel Index （BI） score. Results： In the 14^Th day the group A was significantly superior to that the group B about the SSS score （P 〈 0.05）. In the 90^Th day after the therapy, the group A showed a remarkable improvement in MRS score and BI score （P 〈 0.05）. The outcome of the group A were much better than that of the group B at the end of the study about the significant life dependency and disability （P 〈 0.05）. Conclusions： Compared with conservative therapy in treating 25 -40 mL spontaneous basal ganglia intracerebral hemorrhage,the minimally invasive paracentesis therapy remarkably improved the patients＇ activities of daily life, decreased their dependency and disability rate, indicating that the Minimally invasive paracentesis is a safe and effective method.

关 键 词：脑出血 穿刺术 随机对照试验 

分 类 号：R743.34[医药卫生—神经病学与精神病学]