孕妇血清HBV-DNA含量在母婴传播中的意义  

Relationship between Serums HBV-DNA Levels on Pregnant Women and HBV Transmission between Mothers and Infants

作　　者：马静[1] 隋景玉[1] 白宝敏[1] 王娟[1] 符丽华[1] 

机构地区：[1]广东省中山市博爱医院感染科,528403

出　　处：《实用全科医学》2007年第5期395-396,共2页Applied Journal Of General Practice

摘　　要：目的探讨孕妇血清不同HBV-DNA含量与母婴传播率之间的关系。方法用荧光定量PCR方法分别检测96对母婴血清HBV-DNA含量,根据孕妇血清不同HBV-DNA含量进行分组。结果随母血HBV-DNA含量上升,婴儿脐血HBV-DNA含量随之升高,且婴儿HBV感染率增加。结论HBV母婴传播率受孕妇HBV-DNA含量影响。Objective To investigate the influence of serums HBV-DNA quantity in pregnant women on HBV transmission between mothers and infants. Methods Serum HBV-DNA quantity was performed by fluorescence quantitative PCR in 96 paired mothers and infants. Different groups were divided according to the concentration of serums HBV-DNA. Results The cumulative calculation of different groups of maternal serum HBV-DNA showed that there was a positive correlation of serums HBV-DNA between paired mothers and fetal cord blood,and also the mother-infanttransmisslon rates were higher. Conclusions HBV transmission rates were influenced by maternal serum HBV-DNA concentration.

关 键 词：HBV—DNA 含量 疾病传播 

分 类 号：R575.1[医药卫生—消化系统]