视神经血管母细胞瘤的临床诊断及治疗  

Diagnosis and therapy of hemangioblastoma of optic nerve

作　　者：郑康[1] 吴刚[1] 张海石[1] 鲍旭辉[1] 周翔[1] 黄峰平[1] 

机构地区：[1]复日大学附属华山医院神经外科,上海200040

出　　处：《中华神经医学杂志》2007年第4期372-374,共3页Chinese Journal of Neuromedicine

摘　　要：目的研究视神经血管母细胞瘤的临床特点及治疗方法。方法结合国内外文献报道的16例病例,分析华山医院神经外科手术切除的国内首例单发的颅内段视神经血管母细胞瘤。结果视神经血管母细胞瘤可以发生在视神经的任何部位,首发症状为视力减退及视野缺损,术前与视神经胶质瘤、脑膜瘤的鉴别诊断困难。MRI是较有效的诊断手段。外生型视神经血管母细胞瘤可以完全切除且可以达到视神经及视力保护。结论视神经血管母细胞瘤非常罕见,术前难确诊,绝大多数视神经血管母细胞瘤病人合并有Von Hippel Lindou病,手术切除是唯一治疗方法。Objective To study the clinical characteristics and treatment of optic nerve hemangioblastoma, Methods A 38-year-old man with solitary hemangioblastoma in intracranial segment of optic nerve who was the initial case in our country was treated in Huashan hospital, and analyzed based on the reviews on 17 reported cases of optic nerve hemangioblastoma in the world. Results Optic nerve hemangioblastoma might occur in any segment of the optic nerve. The initial symptoms were progressive visual loss and visual field defect. The preoperative differential diagnosis from optic nerve gliomas or meningeomas was quite difficult. Magnetic resonance imaging could provide more information than other radiological examinations. The hemangioblastoma at the peripheral optic nerve could be removed totally with the preservation of optic nerve and vision. Conclusion Solitary optic nerve hemangioblastoma is extremely rare, and preoperative diagnosis is difficult. The majority of the patients with optic nerve hemangioblastomas are complicated by Von Hippel-Lindou＇s disease. The only way to cure optic nerve hemangioblastomas is surgical treatment.

关 键 词：视神经 血管母细胞瘤 手术治疗 

分 类 号：R739.41[医药卫生—肿瘤]