克罗恩病的血清学标记物  

Serologic markers in Crohn's disease

作　　者：胡晓磊[1] 赵允召[1] 

机构地区：[1]南京大学医学院临床学院(南京军区南京总医院)解放军普通外科研究所,江苏南京210002

出　　处：《医学研究生学报》2007年第4期426-429,433,共5页Journal of Medical Postgraduates

基　　金：江苏省自然科学基金资助项目(批准号:BK2006530)

摘　　要：克罗恩病(CD)的病因仍不明确,但大量证据表明CD患者的免疫系统异常是造成炎症和组织损伤的内在因素,现已明确可以通过血清学标记来预测、监测、治疗许多免疫介导的疾病。寻找理想的非侵入性的炎性肠病(IBD)筛选方法的研究仍在进行,其目的是要找到一种高度特异性、敏感性及预测性的标记或标记物组合。作者就应用血清学标记物在CD发病机制中的作用及诊断的研究进展作一综述。The etiology of Crohn＇ s disease is not clear as yet, many evidences has shown that the dysfunction of the immune system is the internal cause of inflammation and tissue damage. It is identified that many immune diseases can be anticipated, monitored and therapeutic through detecting some specified serological markers. To identify some high specific sensitive and predictable markers and groups, the research of searching an ideal and non-incursive method for differentiating inflammatory bowel diseases from other disease is still undergoing. The current research of five serum immune markers that are usefulness in the diagnosis and management of Crohn＇ s disease are summarized.

关 键 词：克罗恩病 溃疡性结肠炎 炎性肠病 血清学标记物 

分 类 号：R574[医药卫生—消化系统]