瘤周水肿的CT灌注成像与MR灌注成像初步比较研究  

A Preliminary Comparative Study of Peritumoral Edema with Perfusion CT and Perfusion MR Imaging

作　　者：康立清[1] 张云亭[1] 孙世梅[2] 

机构地区：[1]天津医科大学总医院放射科,300052 [2]河北省沧州市中心医院肿瘤科

出　　处：《临床放射学杂志》2007年第4期319-322,共4页Journal of Clinical Radiology

摘　　要：目的比较CT灌注成像和MR灌注成像瘤周水肿区相对脑血容量(rCBV)对鉴别高级别神经上皮肿瘤与转移瘤的价值。资料与方法选取同时行CT灌注成像和MR灌注成像检查的14例高级别神经上皮肿瘤(WHOⅢ、Ⅳ级)和8例转移瘤患者,比较瘤周水肿rCBV的鉴别诊断效果。结果CT灌注成像和MR灌注成像均显示高级别神经上皮肿瘤瘤周水肿区rCBV高于转移瘤者,差异有统计学意义(P<0.05)。二者的受试者工作特性曲线(ROC)下面积分别为0.911和0.929。结论CT灌注成像和MR灌注成像瘤周水肿区rCBV对高级别神经上皮肿瘤与转移瘤的鉴别诊断均具有很高的价值,以MR灌注成像更佳。Objective To compare the diagnostic value of rCBV in peritumoral edema region of high grade tumors of neuroepithelial tissue and metastasis using perfusion CT and perfusion MR imaging. Materials and Methods Both perfusion CT scan and perfusion MR scan were performed in 14 cases of high grade tumors of neuroepithelial tissue and 8 cases of metastasis, the resuits of rCBV in peritumoral edema were analyzed. Results Both perfusion CT and perfusion MR imaging demonstrated that the rCBV in peritumoral edema region was higher in high grade tumors of neuroepithelial tissue than that in metastasis with statistical significance （P 〈 0.05）. The area under the ROC curve was 0.911 for perfusion CT, and 0.929 for perfusion MR imaging respectively. Conclusions The rCBV in peritumoral edema region derived from perfusion CT and perfusion MR imaging have great value in differentiating high grade tumors of neuroepithelial tissue and metastasis, perfusion MR imaging is superior to perfusion CT.

关 键 词：灌注 神经上皮肿瘤 转移瘤 体层摄影术 X线计算机 磁共振成像 

分 类 号：R730.4[医药卫生—肿瘤]