合肥市1997～2005年病毒性肝炎流行病学分析  

Epidemiological analysis of viral hepatitis during 1997～2005 in Hefei

作　　者：吴金菊[1] 叶临湘[2] 马尔健[3] 刘怀珠[3] 苏虹[4] 

机构地区：[1]华中科技大学同济医学院公共卫生学院 [2]华中科技大学公共卫生学院流行病与卫生统计学系,湖北武汉430030 [3]合肥市疾病预防控制中心,安徽合肥230061 [4]安徽医科大学公共卫生学院流行病与卫生统计学系,安徽合肥230032

出　　处：《疾病控制杂志》2007年第2期137-139,共3页Chinese Journal of Disease Control and Prevention

摘　　要：目的分析合肥市1997～2005年病毒性肝炎发病情况和流行规律。方法采用描述流行病学方法和相关回归分析方法。结果合肥市1997～2005年共发生病毒性肝炎24562例,死亡66例,年平均发病率62.64/10万,年平均死亡率0.17/10万,发病率呈逐年下降的趋势。甲型肝炎呈直线下降趋势,发病率与接种率呈高度负相关(r=-0.851,P<0.01);乙型肝炎呈稳中略降的趋势,但15岁以下乙肝的发病率下降明显并与乙肝疫苗接种率呈高度负相关(r=-0.832,P<0.01);丙肝和戊肝呈上升趋势。结论使用疫苗能有效降低甲肝和15岁以下儿童乙肝的发病率。在使用疫苗的同时有针对性地采取防控措施是降低病毒性肝炎发病率的关键。Objective To analyze epidemiological trend of viral hepatitis in Hefei, and study the basis for its preventive intervention. Methods Descriptive epidemiological and correlate analytical method were used. Results 24 562 cases of hepatitis in 9 years were reported, of which 66 died. The average incidence of the disease was 62.46 per 100 000. The death rate was 0.17 per 100 000. The incidence of viral hepatitis showed a downward trend, especially hepatitis A. The vaccination rate and the incidence rate of hepatitis A were negatively related （r= -0. 851, P 〈 0.01 ）. Hepatitis B had no obvious reduction. But the vaccination rate and the incidence rate of hepatitis B were negatively related under 15 years old （r = 0. 832, P 〈 0.01 ）. Hepatitis C and E had obvious rising trend. Conclusions Vaccination can reduce incidence of the disease. Effective measures and vaccination are key to reduce the incidence of viral hepatitis.

关 键 词：肝炎 疾病特征 

分 类 号：R575.1[医药卫生—消化系统] R195.4[医药卫生—内科学]