缺血性脑血管病患者糖尿病和糖调节异常的临床分析  

Diabetes mellitus and impaired glucose regulation in patients with ischemic cerebrovascular disease:a clinical analysis

作　　者：胡志兵[1] 戴建武[1] 曹莹[1] 李翠琼[1] 朱慧芬[1] 

机构地区：[1]广州市第十二人民医院神经科,510620

出　　处：《中国脑血管病杂志》2007年第1期14-17,共4页Chinese Journal of Cerebrovascular Diseases

摘　　要：目的研究缺血性脑血管病患者糖尿病和糖调节异常的临床意义。方法选择656例住院缺血性脑血管病患者进行空腹血糖、糖化血红蛋白等项目检测。检测后分为糖尿病组272例、糖调节异常组173例及血糖正常组211例。对既往未诊断糖尿病而空腹血糖在5.6-6.9mmol/L的患者进行口服葡萄糖耐量试验(OGTT),糖代谢分类采用2003年美国糖尿病学会建议标准。结果656例患者住院前糖尿病的诊断率为17.1%(112/656),住院后系统检查发现糖尿病患病率为41.5%(272/656),糖调节异常率为26.4%(173/656);279例空腹血糖在5.66.9mmol/L的患者中,OGTT发现其中25.4%患者可诊断为糖尿病,糖耐量异常为40.9%,3组患者空腹血糖分别为(8.5±2.4)、(5.6±0.8)及(4.5±0.7)mmol/L,糖化血红蛋白分别为(7.5±2.2)、(5.4±0.7)及(4.3±0.4)%,P均<0.01。结论缺血性脑血管病患者多合并糖尿病或糖调节异常,空腹血糖在5.66.9mmol/L的患者应常规作OGTT检查,以筛查糖代谢异常的患者。Objective To study the clinical significance of diabetes mellitus and impaired glucose regulation in patients with isehemie cerebrovaseular disease. Methods A Total of 656 inpatients with ischemie cerebrovaseular disease were selected for determination of fasting plasma glucose and glyeosylated hemoglobin. They were divided into diabetic （n = 272）, impaired glucose regulation （n = 173 ）, and normal plasma glucose （ n = 211 ） groups. Oral glucose tolerance test （OGTT） was conduced in those who had not been diagnosed as diabetes previously, and their fasting plasma glucose were 5.6 - 6. 9 mmol/L. The American Diabetes Association recommended criteria （ ：2003 ） for glycometabolie categorization were used. Results The diagnostic rate of diabetes in 656 patients before admission was 17. 1% , and after systemic examination in the hospital found that the prevalence of diabetes was 41.5% , and impaired glucose regulation was 26. 4%. Among the 279 patients with fasting plasma glucose 5.6-6. 9 mmol/L, OGTT found that 25.4% of the patients could be diagnosed as diabetes, and impaired glucose regulation was 40. 9%. The fasting plasma glucose levels in the diabetes, impaired glucose regulation, and normal glucose groups were 8. 5 ± 2.4, 5.6 ± 0. 8 and 4. 5 ±0. 7mmo[/L respectively. Their glyeosylated hemoglobin levels were 7.5 ± 2. 2, 5.4 ± 0. 7 and 4. 3 ± 0. 4% , respectively. Conclusion Patients with isehemic eerebrovaseular disease may complicate with diabetes or impaired glucose regulation. The patients whose fasting plasma glucose levels are 5.6-6. 9 mmol/L should have their OGTT examination routinely, so as to screen the patients with diabetes and impaired glucose tolerance.

关 键 词：脑缺血 血糖 葡萄糖耐量试验 

分 类 号：R743.3[医药卫生—神经病学与精神病学] R587.1[医药卫生—临床医学]